Results 101 to 110 of about 17,663 (255)

Direct oral anticoagulants versus warfarin: is new always better than the old? [PDF]

, 2018
About 1.4 British million people are at risk of strokes due to non-valvular atrial fibrillation (AF) necessitating long-term anticoagulation. The vitamin K antagonist, warfarin, has a long half-life and narrow therapeutic range necessitating regular ...
Burn, John, Pirmohamed, Munir
core   +1 more source

Rationalizing Proton Pump Inhibitor Use: Southeast Asia Consensus Recommendations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Proton pump inhibitors (PPIs) are integral to managing many gastrointestinal conditions. However, the prevalent inappropriate PPI prescription across Southeast Asia (SEA) is concerning. Given the absence of locally tailored recommendations to inform clinical practice, this consensus document aims to provide recommendations ...
Somchai Leelakusolvong, Tju Siang Chua, Duc Trong Quach, Andrew Ming‐Liang Ong, Ari Fahrial Syam, Augusto Jose G. Galang, Wee Kooi Cheah, Hang Viet Dao, Jose D. Sollano, Kalwinder Singh Khaira, Phuripong Kijdamrongthum, Rahela Ambaras Khan, Sakkarin Chirapongsathorn, Yeong Yeh Lee   +13 more
wiley   +1 more source

Derivation of the non-inferiority margin for the evaluation of direct oral anticoagulants in the treatment of venous thromboembolism [PDF]

, 2013
BACKGROUND: Direct oral anticoagulants that target a single coagulation factor have been developed as an alternative to standard therapies with heparin and/or vitamin K antagonists. The purpose of this study was to derive non-inferiority margins suitable
Anthonie WA Lensing, Martin H Prins
core   +1 more source

Pharmacological profile of non-vitamin K antagonist oral anticoagulants [PDF]

African Journal of Pharmacy and Pharmacology, 2017
The non-vitamin K antagonist oral anticoagulants have been approved since 2008 for the prevention of systemic embolism and stroke in patients with non-valvular atrial fibrillation with prior stroke, transient ischemic attack, or CHA2DS2-VASc score ≥2.
openaire   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Vitamin K antagonist use and renal function in pre-dialysis patients

Clinical Epidemiology, 2018
Pauline WM Voskamp,1 Friedo W Dekker,1 Maarten B Rookmaaker,2 Marianne C Verhaar,2 Willem Jan W Bos,3 Merel van Diepen,1 Gurbey Ocak2 1Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; 2Department of ...
Voskamp PWM, Dekker FW, Rookmaaker MB, Verhaar MC, Bos WJW, van Diepen M, Ocak G   +6 more
doaj  

Stroke and recurrent haemorrhage associated with antithrombotic treatment after gastrointestinal bleeding in patients with atrial fibrillation:nationwide cohort study [PDF]

, 2015
Study question What are the risks of all cause mortality, thromboembolism, major bleeding, and recurrent gastrointestinal bleeding associated with restarting antithrombotic treatment after gastrointestinal bleeding in patients with atrial fibrillation ...
Bonde, Anders N., Fosbøl, Emil L., Gislason, Gunnar H., Gundlund, Anna, Hansen, Morten L., Lindhardt, Tommi B., Lip, Gregory Y.H., Olesen, Jonas B., Pallisgaard, Jannik L., Staerk, Laila, Torp-Pedersen, Christian   +10 more
core   +2 more sources

Non–Vitamin K Antagonist Oral Anticoagulants in Patients With Atrial Fibrillation and Thrombocytopenia

Journal of Cardiovascular Pharmacology, 2018
Aims: Thrombocytopenia was one of the exclusion criteria in randomized trials in which non–vitamin K antagonist oral anticoagulants (NOACs) were tested. The safety of NOACs in patients with atrial fibrillation (AF) and thrombocytopenia remains unclear.
Janion-Sadowska, Agnieszka, Papuga-Szela, Elżbieta, Łukaszuk, Robert, Chrapek, Magdalena, Undas, Anetta   +4 more
openaire   +3 more sources

Evaluation of Self‐Reported Confidence Levels of Final Year Dentistry Students at the University of Queensland in Oral Surgery and General Medicine

Oral Surgery, EarlyView.
ABSTRACT Objective This study aimed to investigate the self‐reported confidence levels of final year dental students at the University of Queensland, Australia, in oral surgery procedures and general medicine to locate gaps in knowledge and aid in improving the dental curriculum.
Hsin‐Chen Lee, Yujia Wang, Sasha Vladimirova, Jessica Zachar, Sowmya Shetty   +4 more
wiley   +1 more source