Results 151 to 160 of about 31,914 (284)

A Chromatographic Approach for Simultaneous Quantification of Multiple Anticoagulants in Human Plasma Samples

Journal of Separation Science, Volume 49, Issue 2, February 2026.
ABSTRACT Anticoagulants are essential drugs for preventing and treating thromboembolic conditions by inhibiting blood clot formation. Warfarin, a vitamin K antagonist, is among the most prescribed agents but presents limitations, including a narrow therapeutic window and a high risk of adverse events, requiring strict monitoring to ensure both safety ...
Federica Guidetti, Sara R. Fernandes, Luisa Barreiros, Marcela A. Segundo   +3 more
wiley   +1 more source

Duplicate Prescription Patterns in Patients With Substance Use Disorders

Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.
ABSTRACT This study sought to investigate the frequency and characteristics of duplicate prescriptions (DPs) in psychiatric inpatients with substance use disorders using a DP classification that differentiates between appropriate DPs (ADPs) and potentially inappropriate DPs (PIDPs). The study was conducted as a monocentric retrospective cross‐sectional
Johannes Heck, Benjamin Krichevsky, Martin Schulze Westhoff, Konstantin Fritz Jendretzky, Martin Klietz, Stephan Greten, Alexander Glahn, Stefan Bleich, Sebastian Schröder   +8 more
wiley   +1 more source

Recurrent haemorrhage, due to vitamin K‐dependent coagulopathy, as the primary presenting complaint in a dog with naturally occurring hypoadrenocorticism

Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 5‐year‐old male neutered standard poodle, presented with recurrent gingival margin haemorrhage and associated prolongations in prothrombin time and activated partial thromboplastin time, with repeatable demonstration of clinical (bleeding) and laboratory (prothrombin time, activated partial thromboplastin time) resolution with, and relapse ...
Jenny Reeve, Aiden Pang
wiley   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, Volume 12, Issue 1, Page 25-55, February 2026.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source

Use of idarucizumab in reversing dabigatran anticoagulant effect: a critical appraisal

Therapeutics and Clinical Risk Management, 2018
Marco Proietti,1–3 Giuseppe Boriani4 1Department of Neuroscience, IRCCS – Istituto di Ricerche Farmacologiche “Mario Negri”, Milan, Italy; 2Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK ...
Proietti M, Boriani G
doaj  

Self-reported treatment burden: A comparison between vitamin K and non-vitamin K oral anticoagulants

Exploratory Research in Clinical and Social Pharmacy
Introduction: Treatment burden (TBN) refers to the impact of patients' healthcare-related workload on their functioning and well-being. A high TBN has been associated with lower adherence to treatment and increased risk of major adverse events, and ...
Miroslav Mihajlovic, Nevena Zec, Jelena Simic, Aleksandar Mihajlovic, Milan Marinkovic, Nebojsa Mujovic, Tatjana Potpara   +6 more
doaj   +1 more source

Relation of the stress hyperglycaemia ratio to residual risk in anticoagulated patients with atrial fibrillation: A report from the prospective Murcia AF Project III cohort

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1431-1442, February 2026.
Abstract Introduction Atrial fibrillation (AF) carries residual thromboembolic and cardiovascular risk despite oral anticoagulation (OAC). The stress hyperglycaemia ratio (SHR), derived from admission glucose and glycated haemoglobin (HbA1c), integrates information on both acute glycaemic fluctuations and chronic glycaemic burden.
Eva Soler‐Espejo, Yang Chen, José Miguel Rivera‐Caravaca, José Antonio Sánchez‐Salas, María Asunción Esteve‐Pastor, Francisco Marín, Vanessa Roldán, Gregory Y. H. Lip   +7 more
wiley   +1 more source

Assessing Cardiac Mechanical Dysfunction in Transfusion‐Dependent β‐Thalassemia With History of Atrial Fibrillation: The Role of Speckle Tracking Echocardiography

Echocardiography, Volume 43, Issue 2, February 2026.
Transfusion dependent β‐thalassemia patients with history of atrial fibrillation (AF) had lower values of global longitudinal strain and peak atrial longitudinal strain (PALS) and showed higher prevalence of both left ventricular and atrial mechanical dysfunction. PALS was associated with high diagnostic accuracy for the detection of AF.
Federico Marchini, Maria Mele, Elena Marchetti, Laura Rotondo, Federica Frascaro, Michele Malagù, Rita Pavasini, Elisabetta Tonet, Matteo Serenelli, Alberto Cossu, Filomena Longo, Maria Lo Monaco, Erika Bertella, Gianluca Campo, Matteo Bertini   +14 more
wiley   +1 more source

The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation.

European Heart Journal, 2018
J. Steffel, P. Verhamme, T. Potpara, P. Albaladéjo, M. Antz, L. Desteghe, K. Haeusler, J. Oldgren, H. Reinecke, V. Roldán-Schilling, N. Rowell, P. Sinnaeve, R. Collins, A. Camm, H. Heidbüchel, G. Lip, J. Weitz, L. Fauchier, D. Lane, G. Boriani, A. Goette, R. Keegan, R. Macfadyen, C. Chiang, B. Joung, W. Shimizu   +25 more
semanticscholar   +1 more source

Polypharmacy in HIV: Rethinking what counts and why it matters

HIV Medicine, Volume 27, Issue 2, Page 186-199, February 2026.
Abstract Polypharmacy, the concurrent use of multiple medications, presents a growing challenge in HIV care as people living with HIV age and experience earlier onset of age‐related co‐morbidities. However, how polypharmacy is defined and assessed in HIV research remains inconsistent.
Luxsena Sukumaran, Alan Winston, Catia Marzolini, Saye Khoo, Marta Boffito, Nadia Naous, Caroline A. Sabin   +6 more
wiley   +1 more source