Results 31 to 40 of about 943,588 (293)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
The Attacks of September 11 in Three Temporalities
The attacks of September 11 are explored from the perspective of three temporalitiesthat of US hegemony (roughly the last 50 years), that of the history of modernity (roughly the last three hundred and ?fty years) and that of the clash between Western
Steven Sherman
doaj +1 more source
Western Movements in Non-Western Worlds
openaire +2 more sources
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The World Bank has been collaborating with parliamentary finance, budget, and public accounts committees in the Western Balkans as part of a knowledge partnership focusing on strengthening financial oversight
World Bank
core +2 more sources
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
World Regional Studies as a Research Framework and Academic Discipline
Dynamic development of international processes at the regional level, various trajectories of regionalization in Europe, Asia, Latin America and other parts of the world created a complex and multidimensional picture of the contemporary international ...
Ekaterina V. Koldunova
doaj +5 more sources
Rethinking Representation: Representative Claims in Global Perspective
The established notion of political representation is challenged on multiple accounts—theoretically, conceptually, and empirically. The contributions to this thematic issue explore the constructivist turn as the means for rethinking political ...
Petra Guasti, Brigitte Geissel
doaj +1 more source
Cultural Interpretation of Dying and Death in a Non-Western Society: The Case of Nigeria
Using Western theories and perspectives as models, this chapter discusses the cultural interpretation of dying and death in a non-Western society. Also discussed, based on the historical, political, and cultural history of Nigeria, are the implications ...
Eyetsemitan, Frank, Frank Eyetsemitan
core +2 more sources

