Results 31 to 40 of about 943,588 (293)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Attacks of September 11 in Three Temporalities

open access: yesJournal of World-Systems Research, 2015
The attacks of September 11 are explored from the perspective of three temporalities—that of US hegemony (roughly the last 50 years), that of the history of modernity (roughly the last three hundred and ?fty years) and that of the ‘clash’ between Western
Steven Sherman
doaj   +1 more source

Western Movements in Non-Western Worlds

open access: yesSuomen Antropologi: Journal of the Finnish Anthropological Society, 2020
  
openaire   +2 more sources

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Performance Framework for Parliamentary Finance, Budget, and Public Accounts Committees in the Western Balkans

open access: yes, 2020
The World Bank has been collaborating with parliamentary finance, budget, and public accounts committees in the Western Balkans as part of a knowledge partnership focusing on strengthening financial oversight
World Bank
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

World Regional Studies as a Research Framework and Academic Discipline

open access: yesVestnik MGIMO-Universiteta, 2016
Dynamic development of international processes at the regional level, various trajectories of regionalization in Europe, Asia, Latin America and other parts of the world created a complex and multidimensional picture of the contemporary international ...
Ekaterina V. Koldunova
doaj   +5 more sources

Rethinking Representation: Representative Claims in Global Perspective

open access: yesPolitics and Governance, 2019
The established notion of political representation is challenged on multiple accounts—theoretically, conceptually, and empirically. The contributions to this thematic issue explore the constructivist turn as the means for rethinking political ...
Petra Guasti, Brigitte Geissel
doaj   +1 more source

Cultural Interpretation of Dying and Death in a Non-Western Society: The Case of Nigeria

open access: yes, 2002
Using Western theories and perspectives as models, this chapter discusses the cultural interpretation of dying and death in a non-Western society. Also discussed, based on the historical, political, and cultural history of Nigeria, are the implications ...
Eyetsemitan, Frank, Frank Eyetsemitan
core   +2 more sources

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