Results 61 to 70 of about 2,708,318 (331)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Non-Western International Relations Theory: Myth or Reality?

open access: yesVestnik RUDN. International Relations, 2017
In recent years, Russian and foreign literature increasingly raises the question on national theories of international relations. A special interest is manifested towards non-Western theories of international relations.
Marina Mikhailovna Lebedeva
doaj   +1 more source

Global Environmental Problems Require Global Solutions : A Case Study in Ecomessianism [PDF]

open access: yes, 1999
Many Western environmental activist groups and theorists have sounded the call for the Earth\u27s salvation from the global environmental crisis. What is lacking, however, is some reflection on the ramifications of framing the problem globally, and on
Galusky, Wyatt, Veak, Tyler
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Typical Islands, Borrowed Islands: Epistemological and Intellectual Decolonialization in Island Studies

open access: yesIsland Studies Journal, 2023
In the emerging scene of non-western island studies, research done on the sinophone world mainly (but not exclusively) by sinophone scholars has become a conspicuous strand in the literature. Despite the diverse locations in focus, most research tends to
Gang Hong
doaj   +1 more source

Editorial : towards an enhancement of knowledge generation in marketing by contributions from non-western contexts [PDF]

open access: yes, 2014
This editorial paper highlights the significance of scholarly contributions from non-western contexts to business and management studies in general and marketing in particular.
Jafari, Aliakbar
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Underperformance in affluence: the remarkable relative decline in American heights in the second half of the 20th-century [PDF]

open access: yes, 2006
Objective: We use the complete set of NHES and NHANES data collected between 1959 and 2004 in order to construct trends for the physical stature of the non-Hispanic white and black US adult population and compare them to those of Western- and Northern ...
Komlos, John, Lauderdale, Benjamin E.
core   +2 more sources

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

From Multiculturalism to Technique: Feminism, Culture and the Conflict of Laws Style [PDF]

open access: yes, 2012
The German chancellor, the French president and the British prime minister have each grabbed world headlines with pronouncements that their state’s policy of multiculturalism has failed.
Knop, Karen   +2 more
core   +3 more sources

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