Results 41 to 50 of about 433,427 (252)

A Population‐Based Study on Childhood Aplastic Anemia—Incidence, Outcomes, and Health‐Related Quality of Life

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Childhood aplastic anemia (AA) is a rare disease, and both the disease itself and its treatment cause significant morbidity. We aimed to determine the contemporary incidence of childhood AA in Finland, to compare the clinical characteristics of AA against inherited bone marrow failure syndromes (IBMFS) and refractory cytopenia of ...
Lauri‐Matti Kulmala   +8 more
wiley   +1 more source

World Regional Studies as a Research Framework and Academic Discipline

open access: yesVestnik MGIMO-Universiteta, 2016
Dynamic development of international processes at the regional level, various trajectories of regionalization in Europe, Asia, Latin America and other parts of the world created a complex and multidimensional picture of the contemporary international ...
Ekaterina V. Koldunova
doaj   +5 more sources

Rethinking Representation: Representative Claims in Global Perspective

open access: yesPolitics and Governance, 2019
The established notion of political representation is challenged on multiple accounts—theoretically, conceptually, and empirically. The contributions to this thematic issue explore the constructivist turn as the means for rethinking political ...
Petra Guasti, Brigitte Geissel
doaj   +1 more source

The Non-Western World

open access: yes, 2004
Through a cross-cultural and multi-disciplinary approach, this introductory textbook focuses on critical issues of development, environment, and cultural conflicts facing most area of the non-Western world. Areas covered include China, Japan, Southeast Asia, the Indian subcontinent, the Middle East, and sub-Saharan Africa.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Are We There Yet? Revisiting the Old and New Postcolonialism(s) in IR

open access: yesHistories
Postcolonialism stands as a synergy between new and old sets of literature that have come together unevenly and in different ways. Postcolonial interventions have contended with IR core themes over the past four decades.
Shelby A. E. McPhee   +2 more
doaj   +1 more source

India and the Non-Western Space: Mapping India’s Potential and Possibilities in South Asia and beyond [PDF]

open access: yesRevista UNISCI
With the dismantling of the Berlin Wall there was a subsequent vocalisation of the end of history thesis, which marked a turning-point in the study of world politics. However, with a gradual transition from a unipolar to an increasingly oligo-polar order,
Tanwir Arshed
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Further Reflections on Samuel P. Huntington’s “Clash of Civilization” and Contemporary Global Politics

open access: yesArụmarụka, 2022
When civilizations clash or encounter one another, it is a general expectation that one of them will necessarily influence or even dominate the other. This has been the principal character of the advent of Euro-Western civilizations across regions of the
Damilola Peter Olatade
doaj   +2 more sources

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