Results 41 to 50 of about 218,438 (267)

θ dependence of Tc in SU(2) Yang-Mills theory

Journal of High Energy Physics
We present an exploratory study to determine the confinement-deconfinement transition temperature at finite θ, T c (θ), for the 4d SU(2) pure Yang-Mills theory.
Norikazu Yamada, Masahito Yamazaki, Ryuichiro Kitano   +2 more
doaj   +1 more source

Color superconductivity on the lattice — analytic predictions from QCD in a small box

Journal of High Energy Physics, 2023
We investigate color superconductivity on the lattice using the gap equation for the Cooper pair condensate. The weak coupling analysis is justified by choosing the physical size of the lattice to be smaller than the QCD scale, while keeping the aspect ...
Takeru Yokota, Yuta Ito, Hideo Matsufuru, Yusuke Namekawa, Jun Nishimura, Asato Tsuchiya, Shoichiro Tsutsui   +6 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

From deconfinement to nuclear matter: mean-field approaches for effective Polyakov loop theories of lattice QCD

Journal of High Energy Physics
Numerical studies of the QCD phase diagram at finite baryon chemical potential μ B on the lattice are impeded by a sign problem. Effective Polyakov loop theories derived from lattice QCD via combined strong-coupling and hopping expansions are valid for ...
Christoph Konrad, Owe Philipsen
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Deconfinement, center symmetry and the ghost propagator in Landau gauge pure SU(3) Yang-Mills theory

Journal of High Energy Physics
The temperature dependence of the Landau gauge ghost propagator is investigated in pure SU(3) Yang-Mills theory with lattice QCD simulations. Its behavior around the confined-deconfined phase transition temperature, T c ∼ 270 MeV, is investigated.
Vítor Paiva, Paulo J. Silva, Orlando Oliveira   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Real-time dynamics of the Schwinger model as an open quantum system with Neural Density Operators

Journal of High Energy Physics
Ab-initio simulations of multiple heavy quarks propagating in a Quark-Gluon Plasma are computationally difficult to perform due to the large dimension of the space of density matrices.
Joshua Lin, Di Luo, Xiaojun Yao, Phiala E. Shanahan   +3 more
doaj   +1 more source

Superconducting Quantum Critical Phenomena [PDF]

Reports in Advances of Physical Sciences, 2018
When the superconducting transition temperature Tc sufficiently approaches zero, quantum fluctuations are expected to be overwhelmingly amplified around zero temperature so that the mean-field approximation may break down.
Yong Tao
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source