Results 61 to 70 of about 781,232 (282)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Propagation Characteristics of Magnetic Tomography Method Detection Signals of Oil and Gas Pipelines Based on Boundary Conditions

Sensors, 2022
The magnetic tomography method (MTM) is a non-contact external inspection method for detecting metal magnetic memory signals. It has great potential for application in long-distance oil pipeline and subsea pipeline inspection.
Linlin Liu, Lijian Yang, Songwei Gao
doaj   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Robust modified passive islanding detection for microgrids using mathematical morphology based dual algorithm

Scientific Reports
The integration of distributed generation (DG) in microgrids has brought the challenge of islanding detection, where a portion of the grid operates independently due to disconnection from the main utility.
Fayez F. M. El-Sousy, Nauman Ali Larik, Wei Lue, Sulaiman Z. Almutairi, Mohammed H. Alqahtani, Saleh Mobayen   +5 more
doaj   +1 more source

Condensed Surfaces of Magnetic Neutron Stars, Thermal Surface Emission, and Particle Acceleration Above Pulsar Polar Caps

, 2008
For sufficiently strong magnetic fields and/or low temperatures, the neutron star surface may be in a condensed state with little gas or plasma above it. Such surface condensation can significantly affect the thermal emission from isolated neutron stars,
D. Lai, Lai, Z. Medin
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Immunofluorescence and targeted removal of the axillary sentinel lymph node in early-stage breast cancer: a simple, safe and effective anatomical approach

Clinical Surgical Oncology
Introduction: The reference technique for axillary sentinel lymph node (SLN) detection in women with breast cancer uses the radioactive marker, technetium (Tc99m), which makes ambulatory surgery difficult and carries a risk of irradiation to the patient ...
Stéphane Lantheaume, Sandrine Soler, Isabelle Ben Taàrit, Anne Le Hémon-Lepaul, Sophie Lantheaume, Céline Lenck, François Sensenbrenner   +6 more
doaj   +1 more source

A Model of High-Frequency Self-Mixing in Double-Barrier Rectifier [PDF]

, 2018
In this paper, a new model of the frequency dependence of the double-barrier THz rectifier is presented. The new structure is of interest because it can be realized by CMOS image sensor technology.
Palma, Fabrizio, Rao, R.
core   +1 more source