Results 41 to 50 of about 1,220,178 (174)

Risk of Age‐Related Ocular Diseases in Non‐Diabetic Adults With Obesity Using Glucagon‐Like Peptide 1 Receptor Agonists

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7580-7591, August 2026.
ABSTRACT Aims To assess whether glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are associated with a lower incidence of age‐related ocular diseases in non‐diabetic older adults with overweight or obesity. Materials and Methods We conducted a retrospective, propensity score–matched cohort study using the TriNetX global research network.
Kuo‐En Chen   +3 more
wiley   +1 more source

Quantification of Vascular Burden on Cranial Vessel Wall Magnetic Resonance Imaging and Ophthalmic Complications in Giant Cell Arteritis

open access: yesACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective There is a need for measures of disease severity for giant cell arteritis (GCA), which may enable identification of high‐risk subgroups (eg, ophthalmic complications) and individualized approaches to therapy. We derived a continuous score using data from cranial vessel wall magnetic resonance imaging (VW‐MRI) to quantify vascular burden in ...
David L. Yang   +15 more
wiley   +1 more source

Is There a Causal Link Between GLP‐1 Receptor Agonists and Non‐Arteritic Anterior Ischaemic Optic Neuropathy? A Critique of the Clinical Evidence

open access: yesClinical &Experimental Ophthalmology, Volume 54, Issue 4, Page 554-564, May/June 2026.
ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are widely used for managing Type 2 diabetes and obesity, with well‐documented and significant cardiometabolic benefits. Recent observational reports and pharmacovigilance data have raised concerns about a possible association between GLP‐1RAs‐particularly semaglutide‐ and non‐arteritic ...
Helen V. Danesh‐Meyer   +1 more
wiley   +1 more source

Effectiveness of Pre‐Transplant Dual GLP‐1 Receptor Agonist and SGLT2 Inhibitor Therapy on All‐Cause Mortality in Organ Transplantation Candidates with Obesity and Type 2 Diabetes: a Target‐Trial Emulation

open access: yesAdvanced Science, Volume 13, Issue 11, 23 February 2026.
This target trial emulation in solid organ transplant candidates with obesity and type 2 diabetes evaluates whether pre‐transplant dual therapy with GLP‐1 receptor agonists plus SGLT2 inhibitors is associated with post‐transplant mortality and kidney graft outcomes compared with monotherapy or usual care, using multinational electronic health records ...
Yu‐Nan Huang   +7 more
wiley   +1 more source

Genome‐Wide DNA Methylation Study Reveals Specific Signatures in the Affected Arterial Tissue of Patients With Giant Cell Arteritis

open access: yesArthritis &Rheumatology, Volume 78, Issue 2, Page 385-393, February 2026.
Objective Giant cell arteritis (GCA) is a large‐vessel vasculitis, potentially causing complications such as blindness and strokes. This study aims to gain insights into the pathogenesis of GCA by identifying specific DNA methylation signatures in the arterial tissue of patients with this vasculitis. Methods DNA methylation profiling was analyzed in 79
Gonzalo Borrego‐Yaniz   +18 more
wiley   +1 more source

Choroidal Thickness in Acute Non-arteritic Anterior Ischemic Optic Neuropathy

open access: yesJournal of Ophthalmic & Vision Research, 2020
Purpose: To compare the choroidal thickness in eyes with acute non-arteritic anterior ischemic optic neuropathy (NAION) with healthy contralateral eye and normal controls.
Homayoun Nikkhah   +5 more
doaj   +1 more source

Giant Cell (Temporal) Arteritis with Anterior Ischemic Optic Neuropathy: A Biopsy-Proven Case in Taiwan

open access: yes, 2011
Giant cell arteritis with arteritic anterior ischemic optic neuropathy has rarely been diagnosed in Taiwan. Recently, we encountered a 76-year- old Taiwanese patient who presented with right visual impairment and marked pale swelling of his right disc ...
鄭成國;李進成;黃楷涵;吳慈恩;彭百慧   +1 more
core   +1 more source

Retrograde Maculopathy or Microcystic Macular Degeneration in Patients With Optic Neuritis due to Neuromyelitis Optica

open access: yesCase Reports in Ophthalmological Medicine, Volume 2026, Issue 1, 2026.
Purpose The aim of this study is to highlight findings of retrograde maculopathy (RM) on optical coherence tomography (OCT) as a sequela of neuromyelitis optica associated optic neuropathy. Observations We report two patients with demyelinating lesions involving the visual pathways due to neuromyelitis optica in whom RM was seen, and in whom the ...
Daniel Kim   +2 more
wiley   +1 more source

Ultrasonography in distinguishing optic neuritis from nonarteritic anterior ischemic optic neuropathy

open access: yesAdvanced Biomedical Research, 2012
Background and Objectives: Optic neuritis (ON) and nonarteritic anterior ischemic optic neuropathy (NAION) have some overlapping clinical profiles.
Alireza Dehghani   +4 more
doaj   +1 more source

Bilateral Non Arteritic Anterior Ischemic Optic Neuropathy Associated With Optic Nerve Head Drusen And Vascular Risk Factors

open access: yesDelhi Journal of Ophthalmology, 2021
We report case history of 52 year old male who presented with sudden painless diminution of vision in right eye and with similar complaint of diminution of vision in left eye six months back.
Eathi Tuli   +3 more
doaj   +1 more source

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