Results 71 to 80 of about 15,499,840 (341)

Noncommunicable disease prevention and control

, 2022
Provisional agenda item 12Annex: Draft Regional Action Framework for Noncommunicable Disease Prevention and Control in the Western ...
Regional Committee for the Western Pacific, 073
core  

Addressing geographical variation in the progression of non-communicable diseases in Peru: the CRONICAS cohort study protocol. [PDF]

, 2012
Background The rise in non-communicable diseases in developing countries has gained increased attention. Given that around 80% of deaths related to non-communicable diseases occur in low- and middle-income countries, there is a need for local knowledge ...
Smeeth, Liam, Miranda, J Jaime, Bernabe-Ortiz, Antonio, CRONICAS Cohort Study Group, Checkley, William, Gilman, Robert H   +5 more
core   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

National and subnational trends of years of life lost and reduced life expectancy caused by bladder cancer in China from 2005 to 2020

BMC Public Health
Background Bladder cancer was commonly diagnosed cancer, which has a high disease burden in China and the world. This study aims to better assess the epidemiological situation of bladder cancer in China.
Zhe Liu, Lingling Yu, Fanshu Yan, Jinlei Qi, Lijun Wang, Maigeng Zhou, Peng Yin   +6 more
doaj   +1 more source

Trends and associated factors in place of death among individuals with cardiovascular disease in China, 2008-2020: A population-based study

The Lancet Regional Health. Western Pacific, 2022
Summary: Background: Cardiovascular disease (CVD) is the leading cause of death (COD) in China. Understanding the characteristics of place of death (POD) among CVD deaths would be of great importance to evaluate the healthcare service utilization at the
Wei Wang, Yunning Liu, Pengpeng Ye, Jiangmei Liu, Peng Yin, Jinlei Qi, Jinling You, Lin Lin, Feixue Wang, Lijun Wang, Yong Huo, Maigeng Zhou   +11 more
doaj   +1 more source

Noncommunicable disease burden among HIV patients in care: a national retrospective longitudinal analysis of HIV-treatment outcomes in Kenya, 2003-2013

BMC Public Health, 2019
BackgroundOver the last decade, the Kenyan HIV treatment program has grown exponentially, with improved survival among people living with HIV (PLHIV). In the same period, noncommunicable diseases (NCDs) have become a leading contributor to disease burden.
Dunstan Achwoka, Anthony K. Waruru, Tai-Ho Chen, Kenneth Masamaro, E. Ngugi, M. Kimani, I. Mukui, J. Oyugi, R. Mutave, T. Achia, A. Katana, L. Ng'ang'a, K. D. de Cock   +12 more
semanticscholar   +1 more source

Convergent communicable and noncommunicable heart disease

, 2011
The 2011 United Nations high-level meeting on prevention and control of noncommunicable diseases (NCDs)1 was an important opportunity to reassess the global response to the escalating epidemic of NCDs.2 Heart diseases with an infectious etiology (for ...
Lyons, J.G., Jasmine G. Lyons, Stewart, S., Simon Stewart   +3 more
core   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

Hepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario, David Sebastián, Mireia Casulleras, Marta Duran‐Güell, Roger Flores‐Costa, Ferran Aguilar, Juan José Lozano, Ingrid W. Zhang, Esther Titos, Jing X. Kang, Antonio Zorzano, Makoto Arita, Joan Clària   +12 more
wiley   +1 more source

Measuring the completeness of death registration in 2844 Chinese counties in 2018

BMC Medicine, 2020
Background Death registration completeness has never been assessed at the county level in China. Such analyses would provide critical intelligence to monitor the performance of the vital registration system and yield adjustment factors to correct death ...
Xinying Zeng, Tim Adair, Lijun Wang, Peng Yin, Jinlei Qi, Yunning Liu, Jiangmei Liu, Alan D. Lopez, Maigeng Zhou   +8 more
doaj   +1 more source