Results 51 to 60 of about 2,891,661 (273)
Physical networks from entropy-driven non-covalent interactions
Nature Communications, 2021 Physical networks typically employ enthalpy-dominated crosslinking interactions that become more dynamic at elevated temperatures. Here, the authors report an entropy-driven physical network based on polymer-nanoparticle interactions that exhibits ...
Anthony C. Yu +5 more
doaj +1 more source
The S66 noncovalent interactions benchmark reconsidered using explicitly correlated methods near the basis set limit [PDF]
, 2017 The S66 benchmark for noncovalent interactions has been re-evaluated using explicitly correlated methods with basis sets near the one-particle basis set limit.
Nitai, Sylvetsky +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Molecules, 2022 Pure organic room-temperature phosphorescence (RTP) materials built upon noncovalent interactions have attracted much attention because of their high efficiency, long lifetime, and stimulus-responsive behavior.
Lingyun Lou +12 more
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Revealing Noncovalent Interactions
, 2016 Molecular structure does not easily identify the intricate noncovalent interactions that govern many areas of biology and chemistry, including design of new materials and drugs.
Paula Mori-Sánchez (2299792) +5 more
core +2 more sources
Advances in Pharmacological and Pharmaceutical Sciences, 2023 This paper investigates the interaction within a liposome-based drug delivery system in silico. Results confirmed that phospholipids, cholesterol, beta-carotene, and vitamin C in the liposome structures interact noncovalently.
D. Hudiyanti +5 more
doaj +1 more source
Molecules, 2023 Noncovalent sulfur interactions are ubiquitous and play important roles in medicinal chemistry and organic optoelectronic materials. Quantum chemical calculations predicted that the electrostatic potentials on the surface of the sulfur atom in organic ...
Ziyu Wang, Weizhou Wang, Hai-Bei Li
doaj +1 more source
Distinguishing Similar Benzyl Radicals via Metal-Mediated Noncovalent Interactions for Csp3–Csp3 Coupling [PDF]
, 2023 The mode that bonding metal catalyst and radical species to carbon-metal greatly enriches the diversities of radical cross coupling, while noncovalent interaction between carbon-centered radical and metal catalyst is seldom revealed, especially in the ...
Zhenyan, Zhao +6 more
core +2 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source