Results 61 to 70 of about 8,693,853 (316)
Toward Reliable Modeling of S-nitrosothiol Chemistry: Structure and Properties of Methyl Thionitrite (CH3SNO), an S-nitrosocysteine Model [PDF]
, 2017 Methyl thionitrite CH3SNO is an important model of S-nitrosated cysteine aminoacid residue (CysNO), a ubiquitous biological S-nitrosothiol (RSNO) involved in numerous physiological processes.
Khomyakov, Dmitry, Timerghazin, Qadir K.
core +3 more sources
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Evaluation of the quality of boreholes water using indicators like Water Quality Index (WQI), and the Comprehensive Pollution Index (CPI) [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعيةMauritania is a country with a water deficit. The majority of these regions are supplied by groundwater through boreholes. Among these regions there is the Wilaya of Akjoujt.
Soughra Dah Soueilem +10 more
doaj +1 more source
None of the Laws But One [PDF]
, 2014 This Symposium contribution explores differences in how congressional Republicans responded to Medicare and how they responded to the Patient Protection and Affordable Care Act (ACA).
Siegel, Neil S.
core +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Modeling and evaluation of a threshing drum under vertical vibration
Journal of Mechanical Engineering and Sciences, 2018 A threshing drum in a power thresher has a main function for separating seeds from stems via threshing teeth. This part undergoes with high exposure of vibrations, which has a greater chance to work improperly and experiences a fatigue failure that can
A. Syuhri +3 more
doaj +1 more source
Spectrophotometric Determination of Tiopronin in Pharmaceutical Preparations [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2001 Two spectrophotometric methods are described for the determination of tiopronin in pharmaceuticals. They are based on the oxidation-reduction reaction between tiopronin and iron (III), then forming a complex between iron (II) and ferrozine or di-2 ...
Maher Abu-Eid +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Journal of Veterinary and Animal SciencesA study was conducted to study the influence of dietary supplementation with Lactobacillus plantarum, Bacillus subtilis, mannan-oligosaccharides (MOS) and their combinations on intestinal immune response in broiler chicken.
Shamna None +8 more
doaj +1 more source