Results 11 to 20 of about 72,059 (284)
Research and developments based on nonhuman primate models have a specific place in biomedical sciences, and nonhuman primate species also have a specific place in the public opinion on the use of animal in research.
Emmanuel Procyk, Martine Meunier
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Background We aimed to prepare a non‐invasive, reproducible, and controllable rat model of intracerebral hemorrhage with focused ultrasound (FUS). Methods A rat intracerebral hemorrhage (ICH) model was established by combining FUS and microbubbles (μBs),
Yao He +13 more
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Modern neuroscience approaches including optogenetics, calcium imaging, and other genetic manipulations have facilitated our ability to dissect specific circuits in rodent models to study their role in neurological disease. These approaches regularly use
Lillian J. Campos +6 more
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Susceptibility of Marmosets (Callithrix jacchus) to Monkeypox Virus: A Low Dose Prospective Model for Monkeypox and Smallpox Disease. [PDF]
Although current nonhuman primate models of monkeypox and smallpox diseases provide some insight into disease pathogenesis, they require a high titer inoculum, use an unnatural route of infection, and/or do not accurately represent the entire disease ...
Eric M Mucker +6 more
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Sharing voxelwise neuroimaging results from rhesus monkeys and other species with Neurovault
Animal neuroimaging studies can provide unique insights into brain structure and function, and can be leveraged to bridge the gap between animal and human neuroscience.
Andrew S. Fox +12 more
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Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future. [PDF]
The respiratory system consists of an integrated network of organs and structures that primarily function for gas exchange. In mammals, oxygen and carbon dioxide are transmitted through a complex respiratory tract, consisting of the nasal passages ...
Miller, Lisa +3 more
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Nonhuman Primate Calorie Restriction [PDF]
Calorie restriction (CR) is the only dietary intervention that repeatedly extends both median and maximal lifespan in a broad range of species. Although there has been considerable interest in CR and its ability to retard aging, the mechanism has remained elusive.
Ricki J, Colman, Rozalyn M, Anderson
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Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes [PDF]
Background Simultaneous inactivation of pig GGTA1 and CMAH genes eliminates carbohydrate xenoantigens recognized by human antibodies. The β4GalNT2 glycosyltransferase may also synthesize xenoantigens.
Adams, A.B. +9 more
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Potential benefits and risks of clinical xenotransplantation [PDF]
The transplantation of organs and cells from pigs into humans could overcome the critical and continuing problem of the lack of availability of deceased human organs and cells for clinical transplantation.
Ayares, D, Cooper, DKC
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Background Autologous transplantation of endothelial progenitor cells (EPCs) is a promising therapeutic approach in the treatment of various vascular diseases. We previously reported a two-step culture system for scalable generation of human EPCs derived
Meng Qin +7 more
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