Results 31 to 40 of about 2,436 (126)
Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen +11 more
wiley +1 more source
A biópsia do linfonodo sentinela no tratamento do câncer de mama vem substituindo a linfadenectomia em casos iniciais. Este tratamento pode ser realizado com o corante azul vital e/ou radiofármaco.
Julia Yoriko Shinzato +5 more
doaj +1 more source
Summary Duckweeds (Lemnaceae) have excellent potential for fundamental and applied research due to ease of cultivation, small size, and continuous fast clonal growth. However, their usage as model organisms and platforms for biotechnological applications is often limited by the lack of universal genetic manipulation methods necessary for transgene ...
Verónica Barragán‐Borrero +12 more
wiley +1 more source
HyperProbe1.1 enables rapid, label‐free biochemical mapping of freshly resected meningiomas. By quantifying endogenous biomarkers such as cytochrome c oxidase, hemoglobin derivatives, and lipids, the system reveals molecular signatures consistent with tumor grading and generates spatial maps that visualize metabolic and vascular heterogeneity across ...
Pietro Ricci +13 more
wiley +1 more source
Abstract This case report presents a recent case of scuticociliatosis in a whitetip reef shark (Triaenodon obesus), housed at a zoo (Haus des Meeres Aqua Terra Zoo, Vienna, Austria). Clinical signs such as uncoordinated swimming and body tilt were observed prior to death.
Hella Schwegler +5 more
wiley +1 more source
A two‐step approach combining laser powder bed fusion of FeSi electrical steel with Bakelite infiltration enables the fabrication of multifunctional gyroid lattice composites. The resulting structures exhibit high strength, magnetic anisotropy, and complete polymer infiltration, demonstrating a simple and scalable route toward lightweight, mechanically
Angelo F. Andreoli +9 more
wiley +1 more source
Tumores papilares intraductales del seno Intraductal papillary tumors of the breast
Introducción. Los tumores papilares intraductales del seno son un grupo heterogéneo de lesiones que se caracterizan por una configuración papilar en el examen macroscópico o microscópico.
Eduardo Torregroza-Diazgranados +1 more
doaj
The molecular co‐chaperone NbSGT1 interacts with potyviral HC‐Pro and promotes viral infection in plants. Notably, (1) NbSGT1 enhances the RSS activity of HC‐Pro and (2) NbSGT1 acts as an endogenous suppressor of RNA silencing (ESR), suppressing RNA silencing in plants.
Wei Shi +8 more
wiley +1 more source
Betulinic acid reduces infection by Staphylococcus aureus biofilms on implants by inhibiting their formation and adhesion, decreasing EPS and eDNA formation and enhancing immune clearance. Simultaneously, it reduces skin tissue inflammation, enhances type I collagen production, and promotes wound healing.
Dongbin Guo +8 more
wiley +1 more source
Overlapping Hyperpigmented and Poikilodermatous Mycosis Fungoides
Primary cutaneous T‐cell lymphomas (pCTCLs) are a heterogeneous group of rare clonal T‐cell disorders, among which mycosis fungoides (MF) is the most common subtype. Several clinicopathologic variants of MF have been described, including poikilodermatous and hyperpigmented forms, with occasional overlap between variants.
Joan Somja +2 more
wiley +1 more source

