Results 111 to 120 of about 2,501,308 (322)

Optical Windows for Transcranial Brain Imaging in Living Mice: Skull Thinning, Clearing, and Beyond

Advanced Science, EarlyView.
Longitudinal, noninvasive in vivo imaging is crucial for studying brain physiology. Advances in transcranial optical windows and multiphoton microscopy have improved imaging depth, but their performance often deteriorates over time. This work investigated various transcranial window approaches and found that skull regrowth limits image quality.
Yiming Fu, Gewei Yan, Zhentao She, Yingzhu He, Kangqi Liu, Jianan Qu   +5 more
wiley   +1 more source

The study of noninvasive brain stimulation using molecular brain imaging: A systematic review

NeuroImage, 2020
Electromagnetic noninvasive brain stimulation (NIBS) techniques, such as transcranial magnetic stimulation and transcranial electrical stimulation, are widely used in research and represent emerging clinical treatment options for many brain disorders ...
Sara Tremblay, L. Tuominen, Vanessa K. Zayed, Á. Pascual-Leone, J. Joutsa   +4 more
semanticscholar   +1 more source

Noninvasive radioelectric asymmetric brain stimulation in the treatment of stress-related pain and physical problems: psychometric evaluation in a randomized, single-blind placebo-controlled, naturalistic study

, 2011
Vania Fontani1, Salvatore Rinaldi1,2, Lucia Aravagli1, Piero Mannu1, Alessandro Castagna1, Matteo Lotti Margotti11Rinaldi-Fontani Institute, 2Medical School of Occupational Medicine, University of Florence, Florence, ItalyBackground: The aim of this ...
Fontani V, Rinaldi S, Aravagli L, Margotti ML, Mannu P, Castagna A   +5 more
core  

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Causal evidence that intrinsic beta frequency is relevant for enhanced signal propagation in the motor system as shown through rhythmic TMS [PDF]

, 2016
Correlative evidence provides support for the idea that brain oscillations underpin neural computations. Recent work using rhythmic stimulation techniques in humans provide causal evidence but the interactions of these external signals with intrinsic ...
Brooks, Joseph L., Bauer, M, Driver, Jon, Bestmann, S, Brooks, Joseph L, Penny, Will, Thut, Gregor, Thut, G, Economides, M, Driver, J, Brooks, JL, Penny, W, Economides, Marcos, Romei, Vincenzo, Bestmann, Sven, Romei, V, Bauer, Markus   +16 more
core   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Noninvasive brain stimulation in rehabilitation of hemispatial neglect after stroke

CNS Spectrums, 2020
Background Noninvasive brain stimulation can modulate neural processing within the motor cortex and thereby might be beneficial in the rehabilitation of hemispatial neglect after stroke.
Jitka Veldema, K. Bösl, G. Neumann, G. Verheyden, D. Nowak   +4 more
semanticscholar   +1 more source

“Self-Neuroenhancement”: The Last Frontier of Noninvasive Brain Stimulation?

Journal of Clinical Neurology, 2020
N ...
Francesco Fisicaro, Giuseppe Lanza, Rita Bella, Manuela Pennisi   +3 more
openaire   +3 more sources

SPARC Drives Podocyte Mitochondrial Damage and Ferroptosis in Diabetic Kidney Disease Following Klotho Deficiency

Advanced Science, EarlyView.
Klotho deficiency promotes podocyte mitochondrial dysfunction and ferroptosis through activation of the PKCα/CUX1/SPARC/TGFβ‐RII axis. SPARC emerges as a key mediator linking Klotho loss to podocyte injury in DKD and other kidney injury models, suggesting broader implications for CKD progression.
Qing Yang, Huimin Jiang, Chenyang Xiong, Xindi Zhou, Qinqin Tan, Han Xiao, Lan Qiu, Chun Gan, Yaxi Chen, Haiping Yang, Wei Jiang, Qiu Li   +11 more
wiley   +1 more source

Consistency of MEPs elicited at two TMS intensities

Brain Stimulation, 2023
Daniel Manning, Recep Ozdemir, Stephanie Buss, Mouhsin Shafi, Peter Fried   +4 more
doaj   +1 more source