Results 41 to 50 of about 884,273 (294)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Nonlinear characterization of half and full wavelength power ultrasonic devices [PDF]
, 2016 It is well known that power ultrasonic devices whilst driven under elevated excitation levels exhibit nonlinear behaviors. If no attempt is made to understand and subsequently control these behaviors, these devices can exhibit poor performance or even ...
Cardoni, Andrea +2 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
IEEE Access, 2022 We consider second order nonlinear systems in control canonical form, where the functional relation between the control variable and the system acceleration is nonlinear, uncertain and discontinuous.
Denis Vasko, Jan Kardos, Eva Miklovicova
doaj +1 more source
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Control of Nonlinear Distributed Parameter Systems Based on Global Approximation [PDF]
Journal of Applied Mathematics, 2014 We extend an iterative approximation method to nonlinear, distributed parameter systems given by partial differential and functional equations. The nonlinear system is approached by a sequence of linear time-varying systems, which globally converges in the limit to the original nonlinear systems considered. This allows many linear control techniques to
Du, Chunyan, Xing, Guansheng
openaire +4 more sources
Thomas decompositions of parametric nonlinear control systems
, 2012 This paper presents an algorithmic method to study structural properties of nonlinear control systems in dependence of parameters. The result consists of a description of parameter configurations which cause different control-theoretic behaviour of the ...
Lange-Hegermann, Markus, Robertz, Daniel
core +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Robust control by non-linear system include uncertain parameters
RUDN Journal of Engineering Research, 2009 In this paper we focus on research of the task of robust non-linear object's control in situation when information about variation of parameters is not fully complete. Necessary and sufficient conditions of stabilization and d-robust control are received.
A N Afanasiev, E R Bovshuk
doaj