A miniaturized drug sensitivity and resistance testing (DSRT) workflow based on the Droplet Microarray (DMA) platform enables functional drug testing using minimal patient‐derived tumor material. By screening nanoliter‐scale droplets containing as few as 300 cells, this approach generates reproducible and tumor‐specific drug response profiles ...
Maryam Salarian +7 more
wiley +1 more source
Nonlinear effects of ambient temperature and treatment days on nocturnal enuresis using generalized additive models. [PDF]
Miyano T +4 more
europepmc +1 more source
Examining the Nonlinear Effects of Residential and Workplace-built Environments on Active Travel in Short-Distance: A Random Forest Approach. [PDF]
Guo L, Yang S, Peng Y, Yuan M.
europepmc +1 more source
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal +7 more
wiley +1 more source
Nonlinear effects of the built environment on urban vitality in Jinan based on multi-source data and explainable AI. [PDF]
Yu M, Ji Q, Zheng X, Cui W.
europepmc +1 more source
Nonlinear Effects of Economic Policy Uncertainty Shocks on Carbon Emissions in China: Evidence from Province-Level Data. [PDF]
Wu C, Liu Z, Liu J, Du M.
europepmc +1 more source
Copper–Collagen Interactions Regulate the Mechanical and Invasive Properties of Tumor Spheroids
Ionic copper is investigated as a modulator of tumor spheroid growth and invasiveness in a 3D microfluidic glioblastoma model. Copper exposure alters metabolic activity, cytoskeletal organization, protrusion dynamics, and EMT‐related phenotypes in a dose‐ and timing‐dependent manner, revealing how copper bioavailability shapes tumor aggressiveness ...
Paula Guerrero‐López +5 more
wiley +1 more source
Nonlinear effects of meteorological factors on foodborne disease outbreaks in yantai from 2014 to 2024. [PDF]
Chen Y +7 more
europepmc +1 more source
Nonlinear Effects Induced by Interactions among Functional Groups of Bacteria and Fungi Regulate the Priming Effect in Malagasy Soils. [PDF]
Jaillard B +3 more
europepmc +1 more source
Microengineered Gradient Hydrogels for Mechanobiology
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong +4 more
wiley +1 more source

