Results 41 to 50 of about 260,232 (317)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Analytical approximate solutions to the nonlinear Fornberg–Whitham type equations via modified variational iteration method

open access: yesPartial Differential Equations in Applied Mathematics
In this paper, we utilize the modified variational iteration method introduced by Abassy et al. for obtaining the analytical approximate solutions of the nonlinear Fornberg–Whitham equation and modified nonlinear Fornberg–Whitham equation.
Md. Asaduzzaman   +2 more
doaj   +1 more source

A Nonlinear Wave Equation with Jumping Nonlinearity

open access: yesDiscrete and Continuous Dynamical Systems, 1998
The authors study multiplicity of solutions \(u(x,t)\) for a piecewise linear perturbation of the one-dimensional wave operator \(u_{tt}-u_{xx}\) under Dirichlet boundary condition on the interval \((-{\pi\over 2}, {\pi\over 2})\) and periodic condition on \(t\), that is \[ \begin{cases} u_{tt}-u_{xx}+g (u)=f(x,t) \text{ in }\left(-{\pi\over 2}, {\pi ...
Choi, Q-Heung, Jung, Tacksun
openaire   +2 more sources

Invariant analysis and explicit solutions of the time fractional nonlinear perturbed Burgers equation

open access: yes, 2015
The Lie group analysis method is performed for the nonlinear perturbed Burgers equation and the time fractional nonlinear perturbed Burgers equation. All of the point symmetries of the equations are constructed.
Wang, Gangwei, Xu, Tianzhou
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Two-point method for solving nonlinear equation with nondifferentiable operator (in Ukrainian) [PDF]

open access: yesМатематичні Студії, 2011
In the paper we study a combined differential-difference method for solving nonlinear equations with non-differentiable operator. The semilocal convergence of the method is investigated and the order of convergence is established.
S. M. Shakhno, H. P. Yarmola
doaj  

Asymptotic Integration of Fractional Differential Equations with Integrodifferential Right-Hand Side

open access: yesMathematical Modelling and Analysis, 2015
In this paper we deal with the problem of asymptotic integration of a class of fractional differential equations of the Caputo type. The left-hand side of such type of equation is the Caputo derivative of the fractional order r ∈ (n − 1, n) of the ...
Milan Medved, Michal Pospisil
doaj   +1 more source

Solitary-wave solutions of the Degasperis-Procesi equation by means of the homotopy analysis method [PDF]

open access: yes, 2010
The homotopy analysis method is applied to the Degasperis-Procesi equation in order to find analytic approximations to the known exact solitary-wave solutions for the solitary peakon wave and the family of solitary smooth-hump waves.
Abbasbandy, S., Parkes, E.J.
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Local convergence of some high order iterative methods based on the decomposition technique using only the first derivative [PDF]

open access: yesSurveys in Mathematics and its Applications, 2017
We present a local convergence analysis of some high order iterative methods based on the decomposition technique using only the first derivative for solving equations in order to approximate a solution of a nonlinear equation.
Ioannis K. Argyros, Santhosh George
doaj  

Home - About - Disclaimer - Privacy