Results 51 to 60 of about 987,859 (318)

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

open access: yesFEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Exact solutions of modified Zakharov–Kuznetsov equation by the homogeneous balance method

open access: yesAin Shams Engineering Journal, 2014
In this article, the homogeneous balance method is used to construct exact traveling wave solutions for the modified Zakharov–Kuznetsov equation using the Riccati equation.
M. Eslami   +2 more
doaj   +1 more source

New dynamical soliton propagation of fractional type couple modified equal-width and Boussinesq equations

open access: yesAlexandria Engineering Journal, 2022
The space–time fractional coupled modified equal-width equation and the coupled Boussinesq equation are a category of fractional partial differential equations, which might be crucial mathematical feathers in nonlinear optics, solid-state physics ...
M. Ayesha Khatun   +4 more
doaj   +1 more source

Asymptotics from scaling for nonlinear wave equations

open access: yes, 2010
We present a scaling technique which transforms the evolution problem for a nonlinear wave equation with small initial data to a linear wave equation with a distributional source.
Asakura F.   +5 more
core   +1 more source

Nonlinear Evolution Equations

open access: yes, 2019
Nonlinear Evolution Equation presents state-of-the-art theories and results on nonlinear evolution equation, showing related mathematical methods and applications. The basic concepts and research methods of infinite dimensional dynamical systems are discussed in detail.
Chen, Fei   +3 more
openaire   +2 more sources

A New Integrable Nonlinear Evolution Equation [PDF]

open access: yesProgress of Theoretical Physics, 1980
Summary: We show that a new integrable nonlinear evolution equation \(iq_ t+(q/\sqrt{1+| q| ^ 2})_ {xx}=0\) is solved exactly by the inverse scattering method. From the Gelfand-Levitan equation, a one-soliton solution is obtained. It is found that a one-soliton solution has two interesting limits, a small amplitude soliton and a bursting soliton.
Shimizu, Toru, Wadati, Miki
openaire   +2 more sources

Global and Regional Temporal Changes in Cross‐Country Inequalities of Site‐Specific Osteoarthritis Burden, 1990 to 2021

open access: yesArthritis Care &Research, EarlyView.
Objective This study examined the global and regional temporal changes in cross‐country inequalities of site‐specific osteoarthritis (OA) burden from 1990 to 2021. Methods Age‐standardized years lived with disability rates (ASYRs) for site‐specific OA across 204 countries and territories were obtained from the Global Burden of Diseases, Injuries, and ...
Haowei Chen   +14 more
wiley   +1 more source

Modeling Asymmetric Interactions in Economy

open access: yesMathematics, 2020
We consider a general nonlinear kinetic type equation that can describe the time evolution of a variable related to an economical state of an individual agent of the system. We assume asymmetric interactions between the agents.
Mirosław Lachowicz, Henryk Leszczyński
doaj   +1 more source

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