Results 191 to 200 of about 640,764 (331)

Compression‐Tension‐Asymmetry and Stiffness Nonlinearity of Collagen‐Matrigel Composite Hydrogels

Advanced Healthcare Materials, EarlyView.
Self‐assembled collagen hydrogel matrices are widely used in tissue engineering applications. These matrices stiffen and contract laterally under tension due to fiber alignment and soften and collapse under compression due to fiber buckling. It is demonstrated that filler materials, such as Matrigel, linearize the mechanical behavior of collagen ...
David Böhringer, Jan Hinrichsen, Radik Gataulin, Sandra Wiedenmann, Marina Spörrer, Selda Sherifova, Paul Steinmann, Gerhard A. Holzapfel, Ben Fabry, Silvia Budday   +9 more
wiley   +1 more source

Pathway-based polygenic risk of Alzheimer's disease highlights immune genes in cognitive decline. [PDF]

Alzheimers Dement (N Y)
Romic E, Karlsson I, Karalija N, Adolfsson AN, Adolfsson R, Kauppi K.   +5 more
europepmc   +1 more source

Nonlinear mixed effects model analysis of the pharmacokinetics of aripiprazole in healthy Japanese males.

Biological and Pharmaceutical Bulletin, 2007
T. Koue, M. Kubo, T. Funaki, T. Fukuda, J. Azuma, M. Takaai, Y. Kayano, Y. Hashimoto   +7 more
semanticscholar   +1 more source

Highly Sensitive Oxidation‐Resistant Degradable Janus Piezoresistive Electronic Skin for Sustainable Wearable Electronics

Advanced Healthcare Materials, EarlyView.
This study presents a highly sensitive, oxidation‐resistant, biocompatible, and degradable Janus piezoresistive electronic skin for sustainable wearable electronics. The electronic skin exhibits sensitive and stable response across a broad pressure range, exceptional oxidation resistance, and Janus wettability.
Joon Kim, Mohammad Zarei, Deristisya Zahra, Yuhan Lee, Daegun Kim, Seung Goo Lee   +5 more
wiley   +1 more source

A Nonparametric Approach to Practical Identifiability of Nonlinear Mixed Effects Models. [PDF]

Bull Math Biol
Cassidy T, Johnston ST, Plank M, Botha I, Flegg JA, Murphy RJ, Hamis S.   +6 more
europepmc   +1 more source

Multivalent Protein Nanorings for Broad and Potent SARS‐CoV‐2 Neutralization

Advanced Healthcare Materials, EarlyView.
A protein‐only, modular multivalent nanoscaffold displaying 20 anchor points, decorated with two different binders (10 of each), targeting the SARS‐CoV‐2 receptor‐binding domain is presented. The construct self‐assembles into stable, biocompatible, homogeneous nanoparticles, exhibit synergistic binding with fM IC50 values. It also detects spike at 9 ng 
Molood Behbahanipour, Carla Goldin, Cecilia Arahi Prato, Ana Luz Paletta, Oriol Bárcenas, Susanna Navarro, Jordi Pujols, Daniel H. Murgida, María Virginia Tribulatti, Sebastián Esperante, Damian Alvarez‐Paggi, Salvador Ventura   +11 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

Advanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins, Samuel L. Hallam, Mariah J. Austin, Adrianne M. Rosales   +3 more
wiley   +1 more source

Associations Between 40-Year Trajectories of BMI and Proteomic and Epigenetic Aging Clocks: Deciphering Nonlinearity and Interactions. [PDF]

Aging Cell
Drouard G, Argentieri MA, Heikkinen A, Ollikainen M, Kaprio J.   +4 more
europepmc   +1 more source

Nonlinear mixed effects model analysis of the pharmacokinetics of routinely administered bepridil in Japanese patients with arrhythmias.

Biological and Pharmaceutical Bulletin, 2006
M. Taguchi, A. Fujiki, Jotaro Iwamoto, H. Inoue, K. Tahara, Katsuya Saigusa, Isao Horiuchi, Yukari Oshima, Y. Hashimoto   +8 more
semanticscholar   +1 more source