Results 81 to 90 of about 5,509 (159)

Novel Inhibitors of Carbonic Anhydrase I and II Identified by High Throughput Virtual Screening and Validated by X‐Ray Crystallography

ChemMedChem, Volume 21, Issue 14, 29 July 2026.
High‐throughput virtual screening identifies novel carbonic anhydrase II ligands from large chemical libraries, enabling rapid hit discovery. Structural validation by X‐ray crystallography confirms the predicted binding modes and reveals key protein–ligand interactions.
Asher L. Brandt, Joseph Venditto, Marta Ferraroni, Claudiu T. Supuran, Andrea Angeli   +4 more
wiley   +1 more source

Vortex Light Bullets Guided by Disclination Defects

Nanophotonics, Volume 15, Issue 14, 27 July 2026.
A new class of stable and thresholdless light bullets carrying vorticity, guided by the disclination defects introduced into Su–Schrieffer–Heeger‐like lattices with a focusing cubic nonlinearity, is reported. Different discrete rotational symmetry of the aperiodic lattice determines the allowed values of the topological charge of the vortex bullets ...
Zhuo Zhang, Sergey K. Ivanov, Yongdong Li, Yaroslav V. Kartashov, Yiqi Zhang   +4 more
wiley   +1 more source

Response of Boreal Winter Atmospheric Blocking to Topographic Forcing Induced by the Tibetan–Iranian Plateau

Journal of Geophysical Research: Atmospheres, Volume 131, Issue 13, 16 July 2026.
Abstract Employing orographic perturbation experiments from a state‐of‐the‐art climate model, this study investigates the topographic forcing associated with the Tibetan–Iranian Plateau (TIP) in modulating Northern Hemisphere boreal winter blocking frequency.
Minghao Yang, Muchen Nan, Wenqi Zhang, Yue Wu, Nengxue Ma, Xiong Chen   +5 more
wiley   +1 more source

Fluorinated Aminopiperidones as Non‐Glutarimide Thalidomide Analogs: Stereodivergent Synthesis and Validation

ChemMedChem, Volume 21, Issue 13, 14 July 2026.
Fluorinated aminopiperidones, designed as non‐glutarimide thalidomide analogs, were synthesized with full regio‐ and stereocontrol. The C*–CF3 used as carbonyl surrogate improved solubility and membrane interactions while abolishing cereblon binding.
Boštjan Adamlje, Tihomir Tomašič, Christian Steinebach, Sebastian Ebeling, Alexander Herrmann, Marcus D. Hartmann, Jessica L. Horner, Kinjal Bhadresha, Cindy H. Chau, William D. Figg, Izidor Sosič, Andrej Emanuel Cotman   +11 more
wiley   +1 more source

Numerical Simulation for the Wave of the Variable Coefficient Nonlinear Schrödinger Equation Based on the Lattice Boltzmann Method

Mathematics
The variable coefficient nonlinear Schrödinger equation has a wide range of applications in various research fields. This work focuses on the wave propagation based on the variable coefficient nonlinear Schrödinger equation and the variable coefficient ...
Huimin Wang, Hengjia Chen, Ting Li
doaj   +1 more source

Exceptional Light Propagation via Generalized Bulk‐Edge Correspondence

Nanophotonics, Volume 15, Issue 13, 13 July 2026.
We show that unlike in electronic systems, localized edge states in topological photonics are governed not only by nontrivial bulk topology, but also by polarization‐dependent light‐line confinement conditions inherent to Maxwell's equations. This fundamentally generalized bulk‐edge correspondence unlocks new regimes of tunable near‐cutoff localization
Heitor da Silva, Sergey K. Ivanov, Isaac Suárez, José R. Salgueiro, Albert Ferrando   +4 more
wiley   +1 more source

Overcoming Computational Bottlenecks in Quantum Hydrodynamics: A Volume‐Based Integral Formalism for Spherical Nanoparticles

Nanophotonics, Volume 15, Issue 13, 13 July 2026.
Numerical modeling of mesoscopic material response models that capture the quantum dynamics of electrons does not have to come with discouraging computational bottlenecks. The main message is that through a shift in perspective in modeling toward integral equation methods and exploiting symmetry‐based arguments, it is possible to capture complicated ...
Christos Mystilidis, Christos Tserkezis, Guy A. E. Vandenbosch, N. Asger Mortensen, Xuezhi Zheng   +4 more
wiley   +1 more source

Dynamical behaviors, chaotic pattern and multiple optical solitons for coupled stochastic Schrödinger–Hirota system in magneto-optic waveguides with multiplicative white noise via Itô calculus

Results in Physics
The primary focus of this study was on exploring the optical soliton solutions and chaotic patterns in magneto-optic waveguides through the coupled stochastic Schrödinger–Hirota equation with multiplicative white noise.
Tianxiu Lu, Lu Tang, Yuanlin Chen, Caiwen Chen   +3 more
doaj   +1 more source

Chaotic pattern and traveling wave solution of the perturbed stochastic nonlinear Schrödinger equation with generalized anti-cubic law nonlinearity and spatio-temporal dispersion

Results in Physics
The main object of this paper is to study the bifurcation, chaotic pattern and traveling wave solution of the perturbed stochastic nonlinear Schrödinger equation with generalized anti-cubic law nonlinearity and spatio-temporal dispersion.
Zhao Li, Chunyan Liu
doaj   +1 more source

Standing waves for discrete nonlinear Schrodinger equations

Electronic Journal of Differential Equations, 2016
The discrete nonlinear Schrodinger equation is a nonlinear lattice system that appears in many areas of physics such as nonlinear optics, biomolecular chains and Bose-Einstein condensates.
Ming Jia
doaj