Results 71 to 80 of about 24,698,590 (380)

Sequential Monte Carlo Methods for System Identification [PDF]

open access: yes, 2015
One of the key challenges in identifying nonlinear and possibly non-Gaussian state space models (SSMs) is the intractability of estimating the system state.
Dahlin, Johan   +6 more
core   +2 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

CRE Solvability, Exact Soliton-Cnoidal Wave Interaction Solutions, and Nonlocal Symmetry for the Modified Boussinesq Equation

open access: yesAdvances in Mathematical Physics, 2016
It is proved that the modified Boussinesq equation is consistent Riccati expansion (CRE) solvable; two types of special soliton-cnoidal wave interaction solution of the equation are explicitly given, which is difficult to be found by other traditional ...
Wenguang Cheng, Biao Li
doaj   +1 more source

The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1

open access: yesFEBS Letters, EarlyView.
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson   +7 more
wiley   +1 more source

Noise Analysis and Modulation Optimization for Nonlinear Visible Light Communication System With Signal-Dependent Noise

open access: yesIEEE Photonics Journal, 2023
This article investigates the characteristics of the signal-dependent noise (SDN) and corresponding modulation design in nonlinear visible light communication (VLC) systems.
Jiaqi Wei   +3 more
doaj   +1 more source

The properties of output frequencies of nonlinear volterra systems [PDF]

open access: yes, 2008
Nonlinear systems usually have complicated output frequencies in the frequency domain. For the class of nonlinear Volterra systems, some interesting properties for system output frequencies are studied in this paper.
Billings, S.A., Jing, X.J., Lang, Z.Q.
core  

Estimation of Power System Inertia Using Nonlinear Koopman Modes

open access: yes, 2018
We report a new approach to estimating power system inertia directly from time-series data on power system dynamics. The approach is based on the so-called Koopman Mode Decomposition (KMD) of such dynamic data, which is a nonlinear generalization of ...
Hamasaki, Ryo   +2 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Propagation of chaos and Poincar\'e inequalities for a system of particles interacting through their cdf [PDF]

open access: yes, 2008
In the particular case of a concave flux function, we are interested in the long time behaviour of the nonlinear process associated to the one-dimensional viscous scalar conservation law.
Jourdain, Benjamin, Malrieu, Florent
core   +5 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

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