Results 81 to 90 of about 407,249 (301)

Association of CDKN2A/B Homozygous Deletion and Extent of Resection With Survival of Patients With WHO CNS5 Grade 4 Astrocytoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives WHO grade 4 astrocytomas are associated with poor prognosis, and their prognostic factors remain controversial. This study aimed to identify the prognostic factors and develop a management algorithm for these patients. Methods This study retrospectively included 151 CNS5 adult grade 4 astrocytomas from two medical centers.
Jiawei Cai   +13 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

How Do Street Landscapes Influence Cycling Preferences? Revealing Nonlinear and Interaction Effects Using Interpretable Machine Learning: A Case Study of Xiamen Island

open access: yesLand
Building cycling-friendly street environments is crucial for promoting sustainable urban mobility. However, existing studies exploring the influence of the built environment on cycling have paid limited attention to the three-dimensional characteristics ...
Pengliang Hu   +5 more
doaj   +1 more source

Nonlinear Absorptions

open access: yesJournal of Functional Analysis, 1993
Let \(A\) be an \(m\)-completely accretive operator in \(L^ 1(\Omega)\), where \((\Omega,{\mathcal B},\mu)\) is a \(\sigma\)-finite measure space. Let \(j: \Omega\times\mathbb{R}\to [0,\infty]\) be measurable in \(x\in\Omega\), convex and lower semicontinuous in \(r\in\mathbb{R}\), with \(j(x,0)=0\).
Benilan, P., Wittbold, P.
openaire   +2 more sources

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

SIMULATION OF SYNCHRONIZATION OF NONLINEAR OSCILLATORS BY THE EXTERNAL FIELD

open access: yesEast European Journal of Physics, 2017
In this paper, the self-consistent model was considered, consisting of a system of oscillators, the coupling between them was assumed to be integral (due to the fields formed as a result of their co-radiation).
V. M. Kuklin   +3 more
doaj  

Principle of the overlay deformations in the theory of creep

open access: yesStructural Mechanics of Engineering Constructions and Buildings, 2019
The aim of the research is to justify in the non-linear statement the overlay principle of fraction creep deformation, known in the linear creep theory as Bolzmann’s principle of superposition. Methods.
Evgeniy A. Larionov   +2 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Volterra Kernel Estimation of White Light LEDs in the Time Domain

open access: yesSensors, 2018
In this paper, we present a time domain method for extracting coefficients of nonlinear Volterra-series kernels for white light-emitting diodes (LED) used both for illumination and visible light communications.
Grzegorz Stepniak   +2 more
doaj   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

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