Genetic Variation in the Testis-Specific GSG3/CAPZA3 Gene Encoding for the Actin Regulatory Protein in Infertile Males [PDF]
アクチンキャッピング蛋白質 GSG3/CAPZA3 は、受精可能な精子の形態形成に重要な役割を担っている。GSG3/CAPZA3 遺伝子は、イントロンレス遺伝子として哺乳類に保存され、マウスにおいてミッセンス変異が精子の減少と形態異常を誘導し、雄性不妊症の原因となることが知られている。日本人において男性不妊症と GSG3/CAPZA3 遺伝子多型の関係を調べるため、261人の男性不妊症患者と139人の妊孕性が確認された男性ボランティアの遺伝子多型を調べた。その結果 ...
Akira TSUJIMURA+7 more
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Reproductive outcome after surgical sperm retrieval and intracytoplasmic sperm injection in couples with male factor sub fertility: a 10-year retrospective observational study [PDF]
Background: To evaluate surgical sperm retrieval (SSR) rate in men with obstructive azoospermia (OA) and non-obstructive azoospermia (NOA) and to compare clinical pregnancy rate (CPR) following ICSI.
Sebastian, Nikhil, Suraj, Jayalakshmi
core +2 more sources
A substantial number of male infertility is caused by azoospermia. However, the underlying etiology and the molecular basis remain largely unknown. Through single-cell (sc)RNA sequencing, we had analyzed testis biopsy samples from two patients with ...
Shitao Chen+9 more
doaj
Azoospermia, cryptozoospermia and necrospermia can markedly decrease the ability of males to achieve pregnancy in fertile females. However, patients with these severe conditions still have the option to be treated by intracytoplasmic sperm injection ...
Ju-Fen Zheng+7 more
doaj +1 more source
The Role of Varicocele Repair in Non-Obstructive Azoospermic Men: A Systematic Review [PDF]
The outcomes of varicocele repair in non-obstructive azoospermic men remain the subject of controversy. Until now, small studies with small number of patients performed make it difficult to assess the efficacy of varicocele surgery in men with non ...
Birowo, Ponco+4 more
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Аналіз випадків азооспермії в пацієнтів медичного центру лікування безпліддя [PDF]
Semen analyses made in Chernivtsi Medical Centre for Infertility Treatment from 2010 to 2013 were studied. Parameters were evaluated according to the WHO 2000 recommendations.
Владиченко, Костянтин Анатолійович
core
Cryopreservation of testicular and epididymal sperm: techniques and clinical outcomes of assisted conception [PDF]
The introduction of the technique of intracytoplasmic sperm injection to achieve fertilization, especially using surgically retrieved testicular or epididymal sperm from men with obstructive or non-obstructive azoospermia, has revolutionized the field of
Gangrade, Bhushan K.
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Sperm cryopreservation protocol for micro-TESE-retrieved sperm
Azoospermia is characterized by the absence of sperm in the ejaculate and is categorized into obstructive azoospermia (OA) and nonobstructive azoospermia (NOA).
Vijay Mangoli+2 more
doaj +1 more source
The role of varicocele treatment in the management of non-obstructive azoospermia
The literature on male reproductive medicine is continually expanding, especially regarding the diagnosis and treatment of infertility due to non-obstructive azoospermia.
Kubilay Inci, Levent Mert Gunay
doaj
Varicocele and non-obstructive azoospermia – where to start?
Background. Male etiology is responsible for nearly half of cases of infertility. Frequency of azoospermia in infertile men reaches 30 %; varicocele is diagnosed in almost 40 % of the patients.
A. Yu. Popova+4 more
doaj +1 more source