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Morphological changes in the testicle in Sertoli cell-only syndrome in men with nonobstructive azoospermia [PDF]
N. G. KulchenkŠ¾
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Clinical management of nonobstructive azoospermia: An update
International Journal of Urology, 2023AbstractApproximately 1% of the general male population has azoospermia, and nonobstructive azoospermia accounts for the majority of cases. The causes vary widely, including chromosomal and genetic abnormalities, varicocele, drugāinduced causes, and gonadotropin deficiency; however, the cause is often unknown.
Teppei Takeshima +6 more
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Current Opinion in Urology, 2000
Nonobstructive azoospermia (NOA) remains a challenging condition in reproductive medicine to manage. The genetic basis of NOA related to partial deletions of the Y-chromosome has been intensely investigated. Such information is of prognostic value and allows more insightful genetic counseling of couples who opt for assisted reproductive technology ...
P T, Chan, P N, Schlegel
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Nonobstructive azoospermia (NOA) remains a challenging condition in reproductive medicine to manage. The genetic basis of NOA related to partial deletions of the Y-chromosome has been intensely investigated. Such information is of prognostic value and allows more insightful genetic counseling of couples who opt for assisted reproductive technology ...
P T, Chan, P N, Schlegel
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Controversies in the management of nonobstructive azoospermia
Fertility and Sterility, 2009The fertility potential of patients with nonobstructive azoospermia (NOA) depends on sperm extraction from the tissue sample and then in vitro fertilization with intracytoplasmic sperm injection (IVF/ICSI). Unfortunately, there is no consensus regarding predictors that can identify nonobstructive azoospermic men with a potentially high yield at the ...
CARPI, ANGELO, SABANEGH E, MECHANICK J.
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Varicocele repair for nonobstructive azoospermia
Current Opinion in Urology, 2012To evaluate the role of varicocelectomy in the management of patients with varicoceles and nonobstructive azoospermia and to review predictors of successful outcomes.Several small, retrospective, noncontrolled studies have documented return of sperm to the ejaculate in up to 56% of men with nonobstructive azoospermia (NOA) following varicocele repair ...
Marc Goldstein, Akanksha Mehta
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Role of varicocelectomy in men with nonobstructive azoospermia
Fertility and Sterility, 2004To evaluate the benefits of varicocelectomy in men with nonobstructive azoospermia.Retrospective review of effect of prior varicocelectomy on sperm retrieval rates in men with nonobstructive azoospermia. Chart review of men with nonobstructive azoospermia who underwent microsurgical varicocelectomy to determine the effect of the procedure on the need ...
Peter N. Schlegel +2 more
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Quantifying Heterogeneity of Testicular Histopathology in Men with Nonobstructive Azoospermia
Journal of Urology, 2021We sought to determine if testicular histopathological heterogeneity is associated with sperm retrieval rates (SRRs) in men with nonobstructive azoospermia (NOA) who are undergoing microdissection testicular sperm extraction (mTESE).All patients undergoing mTESE by a single, high-volume surgeon at a tertiary infertility referral center between 2010 and
Peter N. Schlegel +4 more
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STX2is a causative gene for nonobstructive azoospermia
Human Mutation, 2018STX2 encodes a sulfoglycolipid transporter. Although Stx2 nullizygosity is known to cause spermatogenic failure in mice, STX2 mutations have not been identified in humans. Here, we performed STX2 mutation analysis for 131 Japanese men clinically diagnosed with nonobstructive azoospermia.
Shigeru Nakamura +13 more
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Obstructive and Nonobstructive Azoospermia
2007Defined as the inability to conceive a pregnancy within 12 mo of unprotected regular intercourse, subfertility affects approx 15% of couples in the United States. Of these couples, 40 to 60% or less will have a particular male factor responsible for their difficulty conceiving.
Peter N. Schlegel, Kinloch Nelson
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The changing landscape of nonobstructive azoospermia
Current Opinion in UrologyPurpose of review This article aims to describe new developments in the field of nonobstructive azoospermia biology, diagnostics, biomarkers, and therapeutic strategies. Recent findings Recent studies have investigated the molecular underpinnings of cellular dysfunction that is ...
Laurianne Rita, Garabed, Ryan, Flannigan
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