A comparative cross-platform analysis of cuproptosis-related genes in human nonobstructive azoospermia: An observational study [PDF]
Medicine (Baltimore)This study aimed to identify novel biomarkers associated with cuproptosis in human nonobstructive azoospermia (NOA). We obtained 4 NOA microarray datasets (GSE145467, GSE9210, GSE108886, and GSE45885) from the NCBI Gene Expression Omnibus database and ...
Silin Jiang +7 more
semanticscholar +2 more sources
Diagnostic algorithm in men suspected with nonobstructive azoospermia [PDF]
Asian Journal of AndrologyThis review focuses on the diagnostic algorithm for nonobstructive azoospermia (NOA), a significant male factor contributing to infertility. NOA, characterized by the absence of sperm in the ejaculate, requires a systematic diagnostic approach to ...
Mahdi Bazzi +3 more
doaj +2 more sources
Noninvasive Prediction of Sperm Retrieval Using Diffusion Tensor Imaging in Patients with Nonobstructive Azoospermia [PDF]
J Imaging, 2023 Microdissection testicular sperm extraction (mTESE) is the first-line treatment plan for nonobstructive azoospermia (NOA). However, studies reported that the overall sperm retrieval rate (SRR) was 43% to 63% among men with NOA, implying that nearly half ...
Sikang Gao +8 more
semanticscholar +2 more sources
Factors predicting successful sperm retrieval in men with nonobstructive Azoospermia: A single center perspective [PDF]
Health Science Reports, 2022 Predicting successful sperm retrieval is essential in counseling infertile men with Azoospermia. Objectives To assess the predictors of successful sperm extraction in men with nonobstructive Azoospermia.
Abdulkareem Aljubran +8 more
doaj +2 more sources
Successful Sperm Retrieval and Clinical Pregnancies Following Micro-TESE and ICSI Treatments in Patients with Nonobstructive Azoospermia Due to Various Etiologies [PDF]
Cells(1) Background: Nonobstructive azoospermia (NOA) etiologies affect the sperm retrieval rate (SRR) by microdissection testicular sperm extraction (micro-TESE) and the clinical outcomes following intracytoplasmic sperm injection (ICSI); (2) Methods: We ...
Guangmin Liu +5 more
semanticscholar +2 more sources
ESX1 gene as a potential candidate responsible for male infertility in nonobstructive azoospermia [PDF]
Sci Rep, 2023 Infertility is a problem that affects approximately 15% of couples, and male infertility is responsible for 40–50% of these cases. The cause of male infertility is still poorly diagnosed and treated.
A. Malcher +9 more
semanticscholar +2 more sources
Interaction between Host and Microbes in the Semen of Patients with Idiopathic Nonobstructive Azoospermia [PDF]
Microbiol Spectr, 2023 Idiopathic nonobstructive azoospermia is one of the great challenges in assisted reproductive therapy. Although microdissection testicular sperm extraction technology is currently available, many men with iNOA still face the problem of poor sperm ...
Peigen Chen +8 more
semanticscholar +2 more sources
Clinical management of nonobstructive azoospermia: An update
International Journal of Urology, 2023 Approximately 1% of the general male population has azoospermia, and nonobstructive azoospermia accounts for the majority of cases. The causes vary widely, including chromosomal and genetic abnormalities, varicocele, drug‐induced causes, and gonadotropin
T. Takeshima +6 more
semanticscholar +3 more sources
DNM3OS Enhances the Apoptosis and Senescence of Spermatogonia Associated with Nonobstructive Azoospermia by Providing miR-214-5p and Decreasing E2F2 Expression [PDF]
Anal Cell Pathol (Amst), 2023 Background Nonobstructive azoospermia (NOA) is a complex disease characterized by the spermatogenic dysfunction of testicular tissues. The roles played by long noncoding RNAs (lncRNAs) in NOA pathogenesis have not been extensively studied.
Rui Hua +6 more
semanticscholar +2 more sources
Whole-Exome Sequencing Analysis of Idiopathic Hypogonadotropic Hypogonadism: Comparison of Varicocele and Nonobstructive Azoospermia [PDF]
Reprod Sci, 2023 As a rare disease leading to male infertility, idiopathic hypogonadotropic hypogonadism (IHH) has strong heterogeneity of clinical phenotype and gene mutation. At present, there is no effective diagnosis and treatment method for this disease.
Ziyang Ma +16 more
semanticscholar +2 more sources