Results 31 to 40 of about 23,658 (304)

Convex Optimization in R

open access: yesJournal of Statistical Software, 2014
Convex optimization now plays an essential role in many facets of statistics. We briefly survey some recent developments and describe some implementations of these methods in R .
Roger Koenker, Ivan Mizera
doaj   +1 more source

Nonparametric density estimation for stratified samples [PDF]

open access: yesStatistics & Probability Letters, 2008
We consider a weighted, nonparametric density estimator for stratified samples. We derive the optimal bandwidth using information on within-stratum variances and means. We provide a plug-in bandwidth when all strata are normally distributed. We show that the optimal sampling scheme is stratified sampling proportional to size, irrespective of the ...
openaire   +2 more sources

Legendre polynomial order selection in projection pursuit density estimation

open access: yesLietuvos Matematikos Rinkinys, 2013
Projection pursuit method and its application to probability density estimation is discussed. Method proposed by J.H. Friedman, based on projection density estimation using orthogonal Legendre polynomials, is analysed.
Mindaugas Kavaliauskas
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

A Nonparametric Estimate of a Multivariate Density Function

open access: yesThe Annals of Mathematical Statistics, 1965
Let $x_1, \cdots, x_n$ be independent observations on a $p$-dimensional random variable $X = (X_1, \cdots, X_p)$ with absolutely continuous distribution function $F(x_1, \cdots, x_p)$. An observation $x_i$ on $X$ is $x_i = (x_{1i}, \cdots, x_{pi})$. The problem considered here is the estimation of the probability density function $f(x_1, \cdots, x_p ...
Loftsgaarden, D. O., Quesenberry, C. P.
openaire   +3 more sources

Nonparametric Methods for Volatility Density Estimation [PDF]

open access: yes, 2011
Stochastic volatility modelling of financial processes has become increasingly popular. The proposed models usually contain a stationary volatility process. We will motivate and review several nonparametric methods for estimation of the density of the volatility process.
van Es, B., Spreij, P., van Zanten, H.
openaire   +4 more sources

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Analysis of Option Butterfly Portfolio Models Based on Nonparametric Estimation Deep Learning Method

open access: yesJournal of Function Spaces, 2023
The option butterfly portfolio is the commonly option arbitrage strategy. In reality, because the distribution of the option state price density (SPD) function is not normal and unknown, so the nonparametric deep learning methods to estimate option ...
Xiangyu Ge   +4 more
doaj   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Home - About - Disclaimer - Privacy