Results 61 to 70 of about 19,319 (259)

Nonparametric density estimation using a multidimensional mixture model of Gaussian distributions

Lietuvos Matematikos Rinkinys, 2005
This paper algorithmically and empirically studies five major types of nonparametric multivariate density estimation techniques, where no assumption is made about data being drawn from any of known parametric families of distribution. There is developed
Tomas Ruzgas, Mindaugas Kavaliauskas
doaj   +3 more sources

Nonparametric Method for Modeling Clustering Phenomena in Emergency Calls Under Spatial-Temporal Self-Exciting Point Processes

IEEE Access, 2019
In this paper, a nonparametric spatial-temporal self-exciting point process is proposed to model clustering features in emergency calls. Gaussian kernel density functions are considered.
Chenlong Li, Zhanjie Song, Xu Wang
doaj   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Nonparametric Bayesian inference for multidimensional compound Poisson processes

Modern Stochastics: Theory and Applications, 2015
Given a sample from a discretely observed multidimensional compound Poisson process, we study the problem of nonparametric estimation of its jump size density $r_{0}$ and intensity $\lambda _{0}$.
Shota Gugushvili, Frank van der Meulen, Peter Spreij   +2 more
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Estimation of The Intensity Function of Non-Homogeneous Poisson Process Using Non-Parametric Density Estimation Methods [PDF]

The Egyptian Statistical Journal, 1991
This paper presents a contribution in the non-parametric estimation of the intensity function of non-homogeneous Poison process from the practical point of view. The cumulative distribution functions of the times of successive events are obtained and the
Abdullah Al-Harby, Tarik Amira, Mohamed Habib   +2 more
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HNRNPU K181 Lactylation Drives Cervical Cancer Growth by Upregulating PHGDH and Reprogramming Serine Metabolism

Advanced Science, EarlyView.
Lactate in cervical cancer induces HNRNPU K181 lactylation, opposed by NAA50‐mediated acetylation and suppressed by Pazopanib. This lactylation enhances HNRNPU binding to PHGDH pre‐mRNA exon 1, maintaining exon 1‐containing transcripts and mRNA stability, thereby activating serine metabolism.
Chang Zhang, Qingfei Meng, Hui Jiao, Huixin Liu, Xiangchao Wang, Honglan Zhou, Yishu Wang   +6 more
wiley   +1 more source

Empirical Density Estimation for Interval Censored Data

Austrian Journal of Statistics, 2016
This paper is concerned with the nonparametric estimation of a density function when the data are incomplete due to interval censoring. The Nadaraya-Watson kernel density estimator is modified to allow description of such interval data.
Eugenia Stoimenova
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Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

The benchden Package: Benchmark Densities for Nonparametric Density Estimation

Journal of Statistical Software, 2012
This article describes the benchden package which implements a set of 28 example densities for nonparametric density estimation in R. In addition to the usual functions that evaluate the density, distribution and quantile functions or generate random ...
Thoralf Mildenberger, Henrike Weinert
doaj