Results 41 to 50 of about 3,968,586 (305)

The abstract of doctoral dissertation ‘Some research on hypothesis testing and nonparametric variable screening problems for high dimensional data’

Statistical Theory and Related Fields, 2020
In this thesis, we construct test statistic for association test and independence test in high dimension, respectively, and study the corresponding theoretical properties under some regularity conditions.
Yongshuai Chen, Hengjian Cui
doaj   +1 more source

A Consistent Nonparametric Test for Granger Non-Causality Based on the Transfer Entropy

Entropy, 2020
To date, testing for Granger non-causality using kernel density-based nonparametric estimates of the transfer entropy has been hindered by the intractability of the asymptotic distribution of the estimators. We overcome this by shifting from the transfer
Cees Diks, Hao Fang
doaj   +1 more source

Nonparametric tests of conditional treatment effects [PDF]

, 2009
We develop a general class of nonparametric tests for treatment effects conditional on covariates. We consider a wide spectrum of null and alternative hypotheses regarding conditional treatment effects, including (i) the null hypothesis of the ...
Whang, Yoon-Jae, Whang, Y.-J., Yoon-Jae Whang, Lee, S., Lee, Sokbae, Sokbae (Simon) Lee   +5 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Nonparametric testing of lack of dependence in functional linear models.

PLoS ONE, 2020
An important inferential task in functional linear models is to test the dependence between the response and the functional predictor. The traditional testing theory was constructed based on the functional principle component analysis which requires ...
Wenjuan Hu, Nan Lin, Baoxue Zhang
doaj   +1 more source

Goodness–of–Fit Tests for Bivariate Time Series of Counts

Econometrics, 2021
This article considers goodness-of-fit tests for bivariate INAR and bivariate Poisson autoregression models. The test statistics are based on an L2-type distance between two estimators of the probability generating function of the observations: one being
Šárka Hudecová, Marie Hušková, Simos G. Meintanis   +2 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Statistical Tests of Symbolic Dynamics

Mathematics, 2021
A novel general method for constructing nonparametric hypotheses tests based on the field of symbolic analysis is introduced in this paper. Several existing tests based on symbolic entropy that have been used for testing central hypotheses in several ...
Fernando López, Mariano Matilla-García, Jesús Mur, Manuel Ruiz Marín   +3 more
doaj   +1 more source

Two-sample Bayesian Nonparametric Hypothesis Testing

Bayesian Analysis, 2015
In this article we describe Bayesian nonparametric procedures for two-sample hypothesis testing. Namely, given two sets of samples $\mathbf{y}^{\scriptscriptstyle(1)}\;$\stackrel{\scriptscriptstyle{iid}}{\s im}$\;F^{\scriptscriptstyle(1)}$ and $\mathbf{y}^{\scriptscriptstyle(2 )}\;$\stackrel{\scriptscriptstyle{iid}}{\sim}$\;F^{\scriptscriptstyle( 2)}$,
Chris C. Holmes, François Caron, Jim E. Griffin, David A. Stephens   +3 more
openaire   +5 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source