Results 51 to 60 of about 101,932 (253)

Multi-Task Nonparametric Regression Under Joint Sparsity

open access: yesIEEE Access
This study investigates a multi-task estimation under joint sparsity. We consider estimating multiple functions when functions of interest share common sparsity patterns.
Jae-Hwan Jhong   +2 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Nonparametric Regression Estimation for Multivariate Null Recurrent Processes

open access: yesEconometrics, 2015
This paper discusses nonparametric kernel regression with the regressor being a \(d\)-dimensional \(\beta\)-null recurrent process in presence of conditional heteroscedasticity. We show that the mean function estimator is consistent with convergence rate
Biqing Cai, Dag Tjøstheim
doaj   +1 more source

CURVE ESTIMATION AND ESTIMATOR PROPERTIES OF THE NONPARAMETRIC REGRESSION TRUNCATED SPLINE WITH A MATRIX APPROACH

open access: yesE-Jurnal Matematika, 2022
Regression analysis is one of the statistical analyses used to estimate the relationship between the predictor and the response variable. Data are given in pairs, and the relationship between the predictor and the response variable was assumed to follow ...
NURUL FITRIYANI, I NYOMAN BUDIANTARA
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant   +11 more
wiley   +1 more source

Outliers vs Robustness in Nonparametric Methods of Regression

open access: yesActa Universitatis Lodziensis. Folia Oeconomica, 2018
The article addresses the question of how robust methods of regression are against outliers in a given data set. In the first part, we presented the selected methods used to detect outliers.
Joanna Trzęsiok
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Nonparametric Instrumental Regression [PDF]

open access: yesSSRN Electronic Journal, 2010
Summary: The focus of this paper is the nonparametric estimation of an instrumental regression function \(\varphi\) defined by conditional moment restrictions that stem from a structural econometric model \(E[Y - \varphi (Z)|W]=0\), and involve endogenous variables \(Y\) and \(Z\) and instruments \(W\).
Darolles, Serge   +3 more
openaire   +4 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

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