Results 41 to 50 of about 332,602 (334)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Identifying Factors Influencing the Corrosion Rate of Steel Using Nonparametric Statistics

open access: yesInternational Journal of Electrochemical Science, 2012
Statistical techniques have made it possible to describe the behavior of certain phenomena. Nonetheless, given the difficulty in obtaining adequate data, it is common not to have random and homogeneous samples in order to conduct parametric statistical ...
D. Nieves-Mendoza   +7 more
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

A Clustering Analysis Method With High Reliability Based on Wilcoxon-Mann-Whitney Testing

open access: yesIEEE Access, 2021
As a core step in clustering analysis, distance measurement results can influence clustering accuracy. Existing measurement methods are mostly based on cluster feature information.
Yuan Cheng   +3 more
doaj   +1 more source

Functional single index models for longitudinal data

open access: yes, 2011
A new single-index model that reflects the time-dynamic effects of the single index is proposed for longitudinal and functional response data, possibly measured with errors, for both longitudinal and time-invariant covariates.
Jiang, Ci-Ren, Wang, Jane-Ling
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A Nonparametric Efficiency Analysis of California Cotton Ginning Cooperatives

open access: yesJournal of Agricultural and Resource Economics, 1993
In the spirit of Leamer's commitment to sensitivity analysis, we employ Farrell's nonparametric efficiency methodology and compare our results with those of Sexton, Wilson, and Wann.
Michael R. Caputo, Lori Lynch
doaj   +1 more source

Bayesian nonparametric analysis of reversible Markov chains [PDF]

open access: yes, 2013
We introduce a three-parameter random walk with reinforcement, called the $(\theta,\alpha,\beta)$ scheme, which generalizes the linearly edge reinforced random walk to uncountable spaces.
Bacallado, Sergio   +2 more
core   +2 more sources

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