Results 201 to 210 of about 8,105,492 (290)

Nasal Tuft Cell Markers Are Predictive of Overall Survival in Sinonasal Neuroendocrine and Sinonasal Undifferentiated Carcinomas

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Sinonasal neuroendocrine carcinoma (SNEC) and sinonasal undifferentiated carcinoma (SNUC) are rare aggressive malignancies with no established prognostic markers. Because features of POU2F3+ small cell lung carcinomas have been identified in both tumors, we evaluated immunostaining for POU2F3, a tuft cell transcription factor, and ...
Nikolina Dioufa, Ricardo V. Bruneto, Jennifer E. Douglas, Nithin D. Adappa, James N. Palmer, Noam A. Cohen, Michael A. Kohanski   +6 more
wiley   +1 more source

Serologic Testing for Middle East Respiratory Syndrome Coronavirus and SARS-CoV-2 Cross-Reactive Immune Responses, the Netherlands. [PDF]

Emerg Infect Dis
Te Marvelde MR, Mykytyn AZ, Raadsen MP, Bouffier AHJ, Varela SB, de Vries RD, GeurtsvanKessel CH, Haagmans BL.   +7 more
europepmc   +1 more source

Chitosan-based edible coating produced from an emulsion containing the major constituents of oregano essential oil for the control of sour rot in 'Lima' orange. [PDF]

Braz J Microbiol
da Silva AM, Terao D, Silva ISO, Silva ISO, Bizeto MA, Camilo FF, Queiroz SCDN, Maia AHN, Vilela ESD, Chaim A, Fracarolli JA.   +10 more
europepmc   +1 more source

Expanded characterization of the valproic acid zebrafish larval model of autism spectrum disorder: Insights into dysregulation in the gut

Animal Models and Experimental Medicine, EarlyView.
Meticulous calculation of zebrafish‐equivalent therapeutic valproic acid (VPA) dosage maximized the translational value of the data. Hyposerotonergic tone underpinned an anxiety‐like outcome as a core symptom of autism spectrum disorder (ASD). Compartment‐specific dopaminergic and serotonergic dysregulation in the brain versus gut provided mechanistic ...
Lesha Pretorius, Johanna Adriana Coetzee, Alexio Pedro dos Santos, Carine Smith   +3 more
wiley   +1 more source

<i>Mycobacterium tuberculosis</i> suppresses protective Th17 responses during infection. [PDF]

Elife
Zilinskas A, Balakhmet A, Fox D, Ni HM, Agudelo C, Samani H, Stanley SA.   +6 more
europepmc   +1 more source

Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder. [PDF]

Genet Epidemiol, 2011
Jiang Y, Zhang H.
europepmc   +1 more source

Patient‐Derived Fibroblasts as a Clinically Relevant Model of Kearns–Sayre Syndrome

Annals of Neurology, EarlyView.
Objective Kearns–Sayre syndrome (KSS) is characterized by single large‐scale mitochondrial DNA deletions and by severe early‐onset clinical manifestations with neurological involvement. Reliable disease models, as well as validated biomarkers or effective treatments, are lacking.
Laura Valls‐Roca, Adrià Vilaseca‐Capel, Judith Cantó‐Santos, Ester Tobías, Félix Andújar‐Sánchez, Laia Farré‐Tarrats, Frederic Tort, Carles Rentero, Carlos Enrich, Virginia López, Juan R. Tejedor, Anna Esteve‐Codina, Cristina Núñez de Arenas, Pedro J. Moreno‐Lozano, José C. Milisenda, Mar O'Callaghan, Teresa García‐Silva, Montserrat Morales‐Conejo, Mario F. Fraga, Rafael Artuch, Miguel Á. Martín, José M. Cuezva, Ana Matas, Glòria Garrabou, Mariona Guitart‐Mampel   +24 more
wiley   +1 more source

Nanomaterial-genetics enables near-infrared-driven genetically targeted neuromodulation. [PDF]

Sci Adv
Liu Y, Wang X, Yin W, Chen J, Fan Y, Yang J, Wang Y, Ge L, Rao W, Wang L, Li C, Guo ZV, Liu N, Sun X, Yang Y.   +14 more
europepmc   +1 more source

Rate and Shape of Functional Decline in Amyotrophic Lateral Sclerosis Identify Clinically Distinct Amyotrophic Lateral Sclerosis Phenotypes

Annals of Neurology, EarlyView.
Objective The ALS Functional Rating Scale–Revised decline rate compresses trajectory shape into a single number, potentially missing distinct phenotypes. We tested whether shape identifies phenotypes that rate does not distinguish, and whether post‐hoc analysis recovers a hidden ultrarapid subgroup. Methods From the Piemonte and Valle d'Aosta register (
Andrea Calvo, Cristina Moglia, Antonio Canosa, Umberto Manera, Elisabetta Zucchi, Giulia Gianferrari, Ilaria Martinelli, Gabriele Mora, Sara Cabras, Francesca Palumbo, Enrico Matteoni, Giorgio Pellegrino, Emilio Minerva, Daniela Pascariu, Stefano Callegaro, Fabrizio D'Ovidio, Rosario Vasta, Letizia Mazzini, Fabiola De Marchi, Jessica Mandrioli, Adriano Chiò   +20 more
wiley   +1 more source

Graph-based pangenome analysis uncovers structural and functional impacts of allopolyploidization events. [PDF]

Sci Adv
Loegler V, Friedrich A, Schacherer J.
europepmc   +1 more source