Two New Species Of Brachycephalus (anura: Brachycephalidae) From The Atlantic Forest In Paraná State, Southern Brazil [PDF]
, 2015 Two new species of brachycephalid frogs are described from Pico Marumbi, municipality of Morretes, and Pico da Igreja, municipality of Guaratuba, Paraná State, southern Brazil.
Haddad C.F.B. +3 more
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A New Species Of Brachycephalus From The Atlantic Rain Forest In São Paulo State, Southeastern Brazil (amphibia: Anura: Brachycephalidae) [PDF]
, 2015 We describe a new toadlet species of the genus Brachycephalus from the Atlantic rain forest in the State of São Paulo, in southeastern Brazil. Specimens were collected from the leaf litter at approximately 750 m above sea level.
Clemente-Carvalho R.B.G. +3 more
core +1 more source
Contribución al estudio de las metodologías de cálculo realista con incertidumbre (BEPU), dentro del análisis determinista de seguridad de plantas nucleares [PDF]
, 2016 El análisis determinista de seguridad (DSA) es el procedimiento que sirve para diseñar sistemas, estructuras y componentes relacionados con la seguridad en las plantas nucleares.
Mendizábal Sanz, Rafael
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New nonparametric approaches for multivariate and functional data analysis in outlier detection, construction of tolerance tubes, and clustering [PDF]
, 2016 Recent advances of powerful computing and data acquisition technologies have made large complex datasets ever-present, including high-dimensional or functional data.
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Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Developments in long distance commuting to London [PDF]
, 2005 The stimulus for this work is the development in long distance commuting to Greater London, from areas beyond the South East Region, which has been increasing since the early nineteen fifties.
Franklin, G, Franklin, G.
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Advanced Science, EarlyView.Multi‐omics analyses uncover breed‐specific cis‐regulatory landscapes and higher‐order chromatin architectural differences that underlie early postnatal muscle fiber divergence in pigs. A super‐enhancer upstream of PPP3CB recruits MEF2C to activate PPP3CB transcription, while the PPP3CB–MEF2C positive feedback loop promotes oxidative muscle fiber ...
Shuailong Zheng +8 more
wiley +1 more source
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Advanced Science, EarlyView.Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes
Advanced Intelligent Discovery, EarlyView.To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song +6 more
wiley +1 more source
Data-based mathematical modeling: Development and application [PDF]
, 1995 This research study presents the mathematical basis for building the MC-HARP data-processing environment. The MC-HARP strategy determines the functional structure and parameters of a mathematical model simultaneously. A Monte Carlo (MC) strategy combined
Banan, Mahmoud-Reza
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