Assessment of Comorbidity and Use of Prescription and Nonprescription Drugs in Patients Above 65 Years Attending Family Medicine Outpatient Clinics [PDF]
Background and aim: Aging is often accompanied by chronic diseases, comorbidity, and polypharmacy. Use of prescription/nonprescription drugs, and over-the-counter (OTC) drugs seen frequently in the elderly.
Münevver Kurt MD, PhD +2 more
doaj +3 more sources
Review of Challenges in Performing Real-World Evidence Studies for Nonprescription Products [PDF]
Christian Maihöfner,1 Theresa Mallick-Searle,2 Jan Vollert,3 Pranab Kalita,4 Vidhu Sood Sethi5 1Department of Neurology, General Fürth Hospital, University of Erlangen, Fürth, Germany; 2Division of Pain Medicine, Stanford Health Care Pain Management ...
Maihöfner C +4 more
doaj +4 more sources
Impact of Delisting Non-Prescription Medicines from Health Insurance Coverage on Physicians’ Prescribing Behaviour in Iran: A Qualitative Study [PDF]
Objective: In June 2018, Iran’s national health insurance policy excluded coverage for 79 nonprescription medicines (NPM) for outpatients aged over 12 years. Since physicians play a crucial role in healthcare delivery, this qualitative study explored how
Mohammad Mahdi Raeis Zadeh +4 more
doaj +2 more sources
QT Myopia and Cardiac Safety: Expanding the Aperture of Arrhythmia Assessment in Early Phase Drug Development. [PDF]
ABSTRACT Regulatory agencies such as the Food and Drug Administration (FDA), European Medicines Agency (EMA), Health Canada, and the Japanese Pharmaceutical and Medical Device Agency (PMDA) provide scientific and public health guidance with cardiac safety being paramount in drug development of new investigational products (IP).
Lester RM, Clark K, Paglialunga S.
europepmc +2 more sources
Managing Drug-Drug Interactions Involving the Non-Prescription Opioid Loperamide Through Physiologically Based Pharmacokinetic Modeling. [PDF]
ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhou Z +6 more
europepmc +2 more sources
Background and Aims Self‐medication, while convenient for managing minor illnesses, poses significant public health risks when practiced without adequate knowledge or oversight.
Salma Sultana +2 more
doaj +2 more sources
Using Medicinal Plants among Patients with Cardiovascular Diseases and Their Related Factors: A Cross-Sectional Study [PDF]
Introduction: The use of medicinal plants (MP) is increasing among the general population and patients with cardiovascular diseases (CVD). Simultaneous use of MP and cardiac medications can cause drug interactions and serious complications.
Mostafa Gholami +3 more
doaj +1 more source
Background Yemen’s health system has severely deteriorated due to the ongoing civil war accompanied by the COVID-19 pandemic which coincided with other outbreaks of endemic infections.
Ebtesam A. Saleh +3 more
doaj +1 more source
Characterization of medication advertisements in a popular US parenting magazine [PDF]
Background: Medication advertisements in magazines typically provide minimal educational benefit. This is of particular concern when targeted to caregivers responsible for making major medical decisions for their children.
Jennifer Mongiovi +2 more
doaj +1 more source
Topical Corticosteroids Misuse: A Burning Issue
Since the introduction of hydrocortisone into dermatology, a tremendous development has occurred in the field of topical corticosteroids. With the growing use of topical corticosteroids, a serious concern for its misuse is to be highlighted. This matter
Saraswoti Neupane
doaj +3 more sources

