Results 61 to 70 of about 359,045 (205)

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 35, 18 September 2026.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim   +9 more
wiley   +1 more source

Vessel identification in diabetic retinopathy [PDF]

open access: yes
Diabetic retinopathy is the single largest cause of sight loss and blindness in 18 to 65 year olds. Screening programs for the estimated one to six per- cent of the diabetic population have been demonstrated to be cost and sight saving, howeverthere are ...
Teng, Thomas Bart
core   +5 more sources

Glycemic Control, Animal Protein Intake, and the Risk of Diabetic Retinopathy Progression Among Patients With Type 2 Diabetes

open access: yesThe Kaohsiung Journal of Medical Sciences, Volume 42, Issue 9, September 2026.
ABSTRACT Effective glycemic control and food consumption play crucial roles in modulating diabetic retinopathy (DR) progression. This observational longitudinal study explored the hemoglobin A1c (HbA1c) and dietary patterns and their associations with the risk and progression of DR among 369 individuals with type 2 diabetes.
Yu‐Ju Wu   +8 more
wiley   +1 more source

Serum Fibroblast Growth Factor 21 Levels Are Correlated with the Severity of Diabetic Retinopathy

open access: yesJournal of Diabetes Research, 2014
The aim of the study was to assess serum fibroblast growth factor 21 (FGF21) concentrations in Chinese type 2 diabetic patients with and without retinopathy and to assess the association between FGF21 and the severity of retinopathy.
Yuan Lin   +13 more
doaj   +1 more source

Case series: The role of retinal ischemia in the pathogenesis and clinical manifestation of diabetic retinopathy

open access: yesOptometry and Vision Science, Volume 103, Issue 8, August 2026.
ABSTRACT Purpose To highlight retinal ischemia as an important component of diabetic retinopathy (DR) pathogenesis, a significant prognostic factor, and a driver of various DR complications, including neovascularization. We aim to describe the main features of ischemic areas that can be identified through fundoscopy, color fundus photography, optical ...
Marina Guro   +6 more
wiley   +1 more source

Alcohol: another risk factor for diabetic retinopathy? [PDF]

open access: yes, 1984
In a five year prospective study clinical features associated with the development and progress of retinopathy were sought in 296 randomly selected diabetic men aged 20-59.
McCulloch, D K   +3 more
core  

A clinical study of the association and risk factors for lower limb neuropathy in patients with diabetic retinopathy

open access: yesJournal of Family Medicine and Primary Care, 2020
Purpose: Association of peripheral neuropathy with diabetic retinopathy is known but the relationship of preclinical neuropathy with various grades of retinopathy is not well documented.
Devika Joshi   +2 more
doaj   +1 more source

Cholesterol accumulation in monocytes is associated with the severity of diabetic complications and the efficacy of glycemic control interventions in patients with type 2 diabetes

open access: yesJournal of Diabetes Investigation, Volume 17, Issue 8, Page 1379-1386, August 2026.
This study reveals that monocyte cholesterol accumulation correlates with the severity of diabetic complications and predicts post‐discharge glycemic deterioration. These findings suggest that monocytic cholesterol serves as a novel translational biomarker reflecting ‘metabolic memory’ and therapeutic resistance in patients with type 2 diabetes ...
Hideyuki Okuma   +3 more
wiley   +1 more source

Treatment of nonproliferative diabetic retinopathy with Defibrotide in noninsulindependent diabetes mellitus, A pilot study [PDF]

open access: yesActa Ophthalmologica Scandinavica, 1999
Microvascular alterations, impairment of coagulation, ischemia and diffuse endothelial damage are related to the progression of diabetic retinopathy. Defibrotide has been demonstrated to produce profibrinolytic, cytoprotective and vasofacilatory activities.
VINGOLO, Enzo Maria   +5 more
openaire   +2 more sources

Choroidal thickness in diabetic patients of Indian ethnicity

open access: yesIndian Journal of Ophthalmology, 2015
Purpose: To evaluate choroidal thickness (CT) change in various grades of diabetic retinopathy (DR) in comparison to age-matched healthy subjects. Methods: This prospective observational study included 227 eyes of 125 subjects with diabetes (study group:
Aditya Sudhalkar   +5 more
doaj   +1 more source

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