Results 241 to 250 of about 142,271 (283)

A genetic algorithm simheuristic for solving the stochastic project portfolio selection problem with portfolio reliability constraints

International Transactions in Operational Research, EarlyView.
Abstract In response to the increasing complexity of modern products, dynamic markets, and intensified competition, project‐based organizations are actively seeking methodologies to efficiently manage their expanding project portfolios. This paper analyzes the project portfolio selection problem in uncertain environments. Despite recent advances in the
Miguel Saiz, David Lopez‐Lopez, Laura Calvet, Angel A. Juan   +3 more
wiley   +1 more source

A novel nonsense mutation c.747C>G in the NEUROD1 gene detected within a Chinese family affected by maturity-onset diabetes of the young type 6. [PDF]

J Diabetes
Li Y, Wen Q, Shao H, Hao M, Sun Y, Liu T.   +5 more
europepmc   +1 more source

Hybrid sorghum breeding in China: A historical review and perspectives

Journal of Integrative Plant Biology, EarlyView.
To commemorate the 60th anniversary of the promotion and application of three‐line hybrid sorghum in China, this review highlights pivotal scientific breakthroughs, systematically summarizes the progress in hybrid sorghum breeding and dwarf sorghum breeding in the country, and presents an outlook on the future of sorghum breeding.
Xiangxiang Meng, Lu Li, Qian Qian, Liang Jiang, Zhaosheng Kong   +4 more
wiley   +1 more source

Know Your Lanes: Unpacking Theoretical Plurality Across Studies of Professions

Journal of Management Studies, EarlyView.
Abstract Professions continue to be central to understanding organizing in the 21st century. The literature on professions is segmented into theoretical conversations that offer different conceptualizations of professions and theoretical concerns. Through an analysis of the literature, we unpack four lanes – teleological, institutional, ecological, and
Ruthanne Huising, Pauli Pakarinen
wiley   +1 more source

Reading Nietzsche in an Age of Conspiracy Theories

Modern Theology, EarlyView.
Abstract This essay considers Friedrich Nietzsche's critique of Christian morality as a template for interpreting the epistemology of modern conspiracy theorists. The first section elucidates Nietzsche's notion of ressentiment as it can be applied to contemporary conspiracism. The effectiveness of this comparative assessment thus raises the question of
J.W. Olson
wiley   +1 more source

Correction of human nonsense mutation via adenine base editing for Duchenne muscular dystrophy treatment in mouse. [PDF]

Mol Ther Nucleic Acids
Jin M, Lin J, Li H, Li Z, Yang D, Wang Y, Yu Y, Shao Z, Chen L, Wang Z, Zhang Y, Zhang X, Wang N, Xu C, Yang H, Chen WJ, Li G.   +16 more
europepmc   +1 more source

Symbiosis‐associated UMAMIT transporters required for establishing efficient nitrogen fixation in Medicago truncatula

New Phytologist, EarlyView.
Summary To address a critical gap in understanding amino acid transport in legume–Rhizobium symbiosis, we investigated the role of symbiosis‐associated USUALLY MULTIPLE ACIDS MOVE IN AND OUT TRANSPORTERS (UMAMITs) in Medicago truncatula nodulation.
Courtney S. Winning, María Isabel Rubia, Wei Liu, Daniel Bronitt, Ángel María Zamarreño, José María García‐Mina, Penelope Smith, Estíbaliz Larrainzar, Michael A. Djordjevic   +8 more
wiley   +1 more source

Unnatural Amino Acid-Based Ionic Liquid Enables Oral Treatment of Nonsense Mutation Disease in Mice. [PDF]

Adv Sci (Weinh)
Shi Y, Shi N, Yang Y, Zheng Z, Xia Q.
europepmc   +1 more source

Expanded Functional Characterization and Optimization of Protein Expression in Treponema denticola Shuttle Plasmids

Molecular Oral Microbiology, EarlyView.
We report optimization of the Treponema denticola shuttle plasmid system by minimizing its size and by characterizing an array of promoter‐gene constructs for genetic complementation, including the first use in Treponema of a Tet‐inducible system for controlled expression of potentially toxic genes.
M. Paula Goetting‐Minesky, Valentina Godovikova, Prakaimuk Saraithong, Alexander H. Rickard, Brigette R. Crawley, Sara M. Agolli, Reagan L. Boyce, Trishna L. Appaji, J. Christopher Fenno   +8 more
wiley   +1 more source