Results 111 to 120 of about 123,545 (295)

Revisiting the Ethics of Urate‐Lowering Therapy Clinical Trials for Gout Management

open access: yes
Arthritis &Rheumatology, EarlyView.
Lisa K. Stamp, Dien Ho, Nicola Dalbeth
wiley   +1 more source

1,1‐Disubstituted Vinylbromides: Versatile Building Blocks for the Synthesis of Nitrogen‐Containing Heterocycles

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
1,1‐Disubstituted vinylbromides are key intermediates for constructing nitrogen‐containing heterocycles. This review provides an overview of the synthetic applications of 1,1‐disubstituted vinylbromides and summarizes recent developments in reaction methodologies, mechanistic insights, and the structural diversity of N‐heterocyclic compounds accessible
Anne Westermeyer   +6 more
wiley   +1 more source

Changes in kidney function in a population with essential hypertension in real life settings [PDF]

open access: yes, 2017
Introduction. Hypertension has been identified as one of the commonest modifiable determinants for chronic kidney disease progression. A variety of antihypertensive drugs are available and their effect on kidney function has been investigated by a ...
Haidich, Anna-Bettina   +6 more
core  

Gender-specific changes in energy metabolism and protein degradation as major pathways affected in livers of mice treated with ibuprofen. [PDF]

open access: yes, 2020
Ibuprofen, an inhibitor of prostanoid biosynthesis, is a common pharmacological agent used for the management of pain, inflammation and fever. However, the chronic use of ibuprofen at high doses is associated with increased risk for cardiovascular, renal,
Gomes, Aldrin V   +5 more
core  

Remarkable Formation of Indene Derivatives Upon Friedel–Crafts Acylation Reactions

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
This shows indene derivatives. Under the reaction conditions of a Friedel–Crafts acylation, alkyl benzenes underwent an unprecedented cyclopentannulation furnishing indene derivatives. Alkylbenzene derivatives react with two equivalents of pivaloyl chloride (PivCl) in the presence of aluminum trichloride under formation of indene derivatives with up to
Leah Bantel   +3 more
wiley   +1 more source

Afebrile vancomycin-induced delayed hypersensitivity suggestive of incomplete drug rash with eosinophilia and systemic symptoms syndrome: a case report

open access: yesJournal of Medical Case Reports
Background Vancomycin-induced delayed hypersensitivity reactions are rare and typically accompanied by systemic symptoms such as fever, eosinophilia, and organ dysfunction, known as drug reaction with eosinophilia and systemic symptoms syndrome. However,
Chien-Hung Chou   +3 more
doaj   +1 more source

Hyponatremia in the 2009 161-km Western States Endurance Run

open access: yes, 2012
Purpose:To determine the incidence of exercise-associated hyponatremia (EAH), the associated biochemical measurements and risk factors for EAH, and whether there is an association between postrace blood sodium concentration ([Na+]) and changes in body ...
Hew-Butler, Tamara   +4 more
core   +1 more source

Acute Renal Failure and Nonsteroidal Anti-Inflammatory Drugs

open access: yesTurkish Journal of Nephrology, 2019
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Tansu SAV
doaj  

Things We Do for No Reason™: Prescribing gabapentinoids for pain

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Gabapentin and pregabalin are among the most frequently prescribed medications in the United States, with gabapentin in the top 10 and pregabalin in the top 100. Despite FDA approval for only select neuropathic conditions, most use is for off‐label pain indications.
Niti G. Patel   +4 more
wiley   +1 more source

Risk of stroke associated with nonsteroidal anti-inflammatory drugs

open access: yesVascular Health and Risk Management, 2014
Ki Park, Anthony A BavryDivision of Cardiovascular Medicine, University of Florida, Gainesville, FL, USAAbstract: Nonsteroidal anti-inflammatory drugs (NSAIDs), both cyclooxygenase (COX)-2-selective and nonselective agents, have been associated with the ...
Park K, Bavry AA
doaj  

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