Results 151 to 160 of about 75,006 (261)

Is Asthma Remission a New Achievable Goal? A Review of the Current Drug‐Related Evidence and Predictors

Allergy, EarlyView.
ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin, Giulia Marcassa, Bianca Olivieri, Gianenrico Senna, Marco Caminati   +4 more
wiley   +1 more source

A ready-to-use deep eutectic solvent-immersed polypropylene fabric cap microextraction strategy for nonsteroidal anti-inflammatory drugs analysis in plasma: a proof-of-concept study. [PDF]

RSC Adv
Dong JY, Wang RJ, Yang XB, Liu YF, Ran Q, Chen D.   +5 more
europepmc   +1 more source

PROSPECT guideline for total hip arthroplasty: updated systematic review and procedure‐specific postoperative pain management recommendations

Anaesthesia, EarlyView.
Summary Introduction The Procedure Specific Postoperative Pain Management (PROSPECT) collaboration develops evidence‐based recommendations integrating analgesic efficacy, safety and functional recovery. Since publication of the 2021 PROSPECT guidelines for total hip arthroplasty, new evidence, particularly on motor‐sparing regional techniques, has ...
Michele Carella, Dario Bugada, Marc Van de Velde, Helene Beloeil, Eric Albrecht, Patricia Lavandhomme, Johan Raeder, Girish P. Joshi, on behalf of the PROSPECT Working Group of the European Society of Regional Anesthesia and Pain Therapy   +8 more
wiley   +1 more source

Exploring Tyramine's Role in the Formation of Supramolecular Adducts with Nonsteroidal Anti-Inflammatory Drugs. [PDF]

Chemistry
Rosso C, Birolo R, Gallo A, Franks WT, Priola E, Chierotti MR, Gobetto R.   +6 more
europepmc   +1 more source

Symptom‐guided reduction of BCG dwell time: findings from the north‐REG randomized trial

BJU International, EarlyView.
Objectives To evaluate the impact of personalized dwell‐time (DT) reductions on symptom prevalence and systemic toxicities in patients undergoing Bacillus Calmette–Guérin (BCG) instillation for non‐muscle invasive bladder cancer (NMIBC). Methods Within a multinational randomized controlled trial (North‐REG Dwell Time Study [NCT04701151]), 225 patients ...
Lene Munk, Josephine Maria Hyldgaard, Vanaja Kumasegaram, Rikke Vilsbøl Milling, Simone Buchardt Brandt, Juan Luis Vásquez, Knud Fabrin, Gitte Wrist Lam, Lasse Bro, Sigurður Gudjonsson, Viveka Ströck, Tomas Jerlsström, Tomas Thiel, Maria Skydt Lindgren, Jørgen Bjerggaard Jensen, Charlotte Graugaard‐Jensen   +15 more
wiley   +1 more source

Effect of nonsteroidal anti-inflammatory drugs on union, opioid utilization, and pain management for tibial fractures (NSAID Trial): a pragmatic randomized clinical trial protocol. [PDF]

OTA Int
Higgins TF, Marchand LS, Thompson RE, Frey KP, Taylor TJ, O'Toole RV, Castillo RC.   +6 more
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

Do nonsteroidal anti-inflammatory drugs increase the risk of atrial fibrillation after non-cardiac surgery? Insights from translational and clinical research. [PDF]

J Anesth Analg Crit Care
Laou E, Mitta S, Voutsadaki E, Ntalarizou N, Tselioti P, Cortegiani A, Chalkias A.   +6 more
europepmc   +1 more source

Direct evidence implicating the asymmetrical dimethylarginine (ADMA)‐dimethylarginine dimethylaminohydrolase 1 (DDAH1) pathway in cerebrovascular dysfunction and stroke pathogenesis in mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Asymmetrical dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS), whereas dimethylaminohydrolase 1 (DDAH1) is primarily responsible for its metabolism. However, the roles of DDAH1 in cerebrovascular regulation are poorly understood. Furthermore, despite evidence that elevated ADMA levels are
Arun Flynn, Alexandra Riddell, Ashton Bernard, Jennifer Haggarty, Stefan Weidt, Jawza Alenazi, Erika Trabold, Delyth Graham, Laura B. Dowsett, James Leiper, Alyson A. Miller   +10 more
wiley   +1 more source

Evaluation of Systemic Nonsteroidal Anti-inflammatory Drugs on Orthodontic Tooth Movement Rate: A Clinical and Biomarker-Based Study.

J Pharm Bioallied Sci
Alam MK, Hajeer MY, Aljubab HMH, Alruwaili EM, AlMashhri JM, Alruwaili RA.   +5 more
europepmc   +1 more source