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Nontypeable Haemophilus influenzae as a Pathogen in Children
Pediatric Infectious Disease Journal, 2009Nontypeable Haemophilus influenzae is a significant pathogen in children, causing otitis media, sinusitis, conjunctivitis, pneumonia, and occasionally invasive infections. H. influenzae type b conjugate vaccines have no effect on infections caused by nontypeable strains because nontypeable strains are nonencapsulated.
Murphy, Timothy F. +7 more
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On the Nature of nontypable Haemophilus influenzae
Antonie van Leeuwenhoek, 1978193 Haemophilus cultures, including 71 nontypable H. influenzae isolates, were examined with respect to phage HP1 sensitivity, lysogeny for this and for other phages and for excretion of bacteriocins. Fifty of the 71 nontypable cultures were sensitive to phage HP1 but only three produced plaques.
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Neonatal Sepsis due to Nontypable Haemophilus influenzae
Archives of Pediatrics & Adolescent Medicine, 1986From August 1980 through July 1984, 19 neonates had sepsis due to Haemophilus influenzae. Onset of disease occurred within 48 hours after birth of all the neonates. One neonate was born at term and 18 were born prematurely, including seven neonates born before 28 weeks' gestation. Eight neonates and one fetus died, six of them within 24 hours of birth.
P, Campognone, D B, Singer
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Nontypeable Haemophilus influenzae
Archives of Internal Medicine, 1982Nontypeable Haemophilus influenzae have generally been regarded as relatively low-grade and infrequent pathogens. These organisms clearly play a role in causing otitis media in children and have been implicated in the pathogenesis of chronic bronchitis. Conflicting data have been presented as to whether nontypeable H influenzae , frequently cause acute
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Developing a nontypeable Haemophilus influenzae (NTHi) vaccine
Vaccine, 2000There is a current high demand for nontypable Haemophilus influenzae (NTHi) vaccines. Various options for the composition of such vaccines are possible. Decisions about the vaccine composition have to take into account the antigenic variability of NTHi, so even complex immunogens such as whole bacteria would preferentially have a tailor-made antigenic ...
Poolman, JT +6 more
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Nontypeable Haemophilus influenzae: challenges in developing a vaccine
Journal of Biotechnology, 1999Nontypeable Haemophilus influenzae (NTHi) is a gram-negative coccobacillus that is one of the bacteria that form the commensal flora of the upper respiratory tract in humans. This bacterium is an important human pathogen causing a broad spectrum of disease in both adults and children, including invasive and localised infections.
Kyd, Jennelle M., Cripps, Allan W.
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A Vaccine for Nontypable Haemophilus influenzae
2003Nontypable H. influenzae (NTHI) is a common commensal of the upper respiratory tract residing in both the nasopharynx and the posterior oropharynx. It is one of the leading causative bacterial pathogens of otitis media (OM) in children and serious urogenital, neonatal and mother-infant infections.
W. Cripps, Allan, M. Kyd, Jennelle
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Adaptive Immunity to Nontypeable Haemophilus influenzae
American Journal of Respiratory and Critical Care Medicine, 2003Abstract Nontypeable Haemophilus influenzae (NTHi) colonizes the upper respiratory tract of most healthy people and is also a major cause of infection in chronic obstructive lung disease. The immune response to this bacterium has not been well characterized.
Paul T, King +5 more
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The pathogenesis of nontypable Haemophilus influenzae otitis media
Vaccine, 2000Nontypable Haemophilus influenzae is a common cause of otitis media and initiates infection by colonizing the upper respiratory tract. In this article, I review our current understanding of the molecular determinants of H. influenzae colonization and discuss the relationship between colonization and otitis media.
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Nontypeable Haemophilus Influenzae Sepsis in a Term Neonate.
The Kobe journal of medical sciences, 2017We reported a term newborn case of early onset sepsis caused by nontypeable Haemophilus Influenzae (NTHi) with massive bacterial invasion in the placenta. Based on the consistent results of maternal placental pathology and neonatal bacterial culture, we diagnosed this as vertical transmission of NTHi via vaginal delivery.
Okubo, Saki +10 more
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