Results 91 to 100 of about 12,649,038 (204)
Report of the Overseas Shipping Conference.
, 1929 Cover title.; (Presented by command: Ordered to be printed, 5th September, 1929).; Covened by the Right Honorable S. M. Bruce, Prime Minister of the Commonwealth of Australia.; "The conference met in Sydney from Thursday, 4th April, till Saturday, 6th ...
Overseas Shipping Conference (1929)
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Vascular normalization confers an endothelial immune suppressive gene expression profile
Molecular Oncology, EarlyView.We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley +1 more source
Przyszłość Unii Europejskiej: możliwe kierunki zmian
PolitejaTHE FUTURE OF THE EUROPEAN UNION: POSSIBLE DIRECTIONS FOR CHANGE The crises of recent years have revealed the weakness of the European Union in many areas.
Danuta Kabat-Rudnicka
doaj +1 more source
2012 IUS Student Conference and Showcase. [Program] [PDF]
, 2012 The IU Southeast Student Conference was organized to allow students, faculty, and visitors to celebrate the achievements of the research and creative projects that are undertaken at IU Southeast. This year there were approximately 225 students displaying
2012 IU Southeast Student Conference
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Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source