Results 261 to 270 of about 255,180 (315)

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

British Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller, Gary Gudelsky, T. John Winhusen, Davide Amato   +3 more
wiley   +1 more source

Timing of Vasopressin Initiation in Patients with Septic Shock: An Updated Systematic Review and Meta-analysis with Trial Sequential Analysis. [PDF]

Indian J Crit Care Med
Bhattacharjee A, Datta PK, Kumar V, Ravikumar RH, Sathe P, Kundu R.   +5 more
europepmc   +1 more source

Absence of Effect of Estrogen on Dopamine, Norepinephrine and .BETA.-Endorphin-Like Immunoreactivity in Human Plasma.

, 1987
Akira Miyake, Takamichi Nishizaki, Shirou Ohtsuka, Yasuhiro Yoshimoto, Toshihiro Aono, Osamu Tanizawa   +5 more
openalex   +2 more sources

3,4‐Methylenedioxymethamphetamine (MDMA) does not induce robust psychomotor activation and 50‐kHz ultrasonic vocalisations in tryptophan hydroxylase 2 (Tph2)‐deficient rats lacking serotonin in the central nervous system

British Journal of Pharmacology, EarlyView.
Background and Purpose 3,4‐Methylenedioxymethamphetamine (MDMA), commonly known as ecstasy, is a psychostimulant with entactogenic properties and known to induce arousal and euphoria. As an amphetamine derivate, MDMA acts on the monoamine systems in the brain and stimulates release of dopamine (DA), noradrenaline (NA) and serotonin (5‐HT), yet their ...
Tianhua Wang, Rainer K. W. Schwarting, Markus Wöhr   +2 more
wiley   +1 more source

Mixed-mechanism analgesics for mixed pain. [PDF]

Front Med (Lausanne)
Raffa RB.
europepmc   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Norepinephrine Onset Time and Mortality in Patients with Septic Shock Treated in the Emergency Department. [PDF]

J Clin Med
Devia Jaramillo G, Motta Hernández JW, Donoso Zapata WG.   +2 more
europepmc   +1 more source

Role of alpha 1-adrenoceptors in norepinephrine-induced cardiomyopathy.

, 1985
J C Lee, D. Phillip Sponenberg
openalex   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Catecholamines Differ in Their Capacity to Form Melanin. [PDF]

MicroPubl Biol
Rayes L, Njus D.
europepmc   +1 more source