Results 11 to 20 of about 180,517 (218)

Overview of the structure and function of the dopamine transporter and its protein interactions

open access: yesFrontiers in Physiology, 2023
The dopamine transporter (DAT) plays an integral role in dopamine neurotransmission through the clearance of dopamine from the extracellular space. Dysregulation of DAT is central to the pathophysiology of numerous neuropsychiatric disorders and as such ...
Binod Nepal   +3 more
doaj   +1 more source

Altered neurocircuitry in the dopamine transporter knockout mouse brain. [PDF]

open access: yesPLoS ONE, 2010
The plasma membrane transporters for the monoamine neurotransmitters dopamine, serotonin, and norepinephrine modulate the dynamics of these monoamine neurotransmitters.
Xiaowei Zhang   +5 more
doaj   +1 more source

Therapeutic Nanobodies Targeting Cell Plasma Membrane Transport Proteins: A High-Risk/High-Gain Endeavor

open access: yesBiomolecules, 2021
Cell plasma membrane proteins are considered as gatekeepers of the cell and play a major role in regulating various processes. Transport proteins constitute a subclass of cell plasma membrane proteins enabling the exchange of molecules and ions between ...
Raf Van Campenhout   +4 more
semanticscholar   +1 more source

SLC6 transporter oligomerization

open access: yesJournal of Neurochemistry, 2020
Transporters of the solute carrier 6 (SLC6) family mediate the reuptake of neurotransmitters such as dopamine, norepinephrine, serotonin, GABA, and glycine.
Kumaresan Jayaraman   +7 more
semanticscholar   +1 more source

Phosphatidylserine transport in cell life and death [PDF]

open access: yesCurrent Opinion in Cell Biology, 2023, Special Issue on Membrane Trafficking, 83, pp.102192, 2023
Phosphatidylserine (PS) is a negatively-charged glycerophospholipid found mainly in the plasma membrane (PM) and in the late secretory/endocytic compartments, where it regulates cellular activity and can mediate apoptosis. Export of PS from the endoplasmic reticulum, its site of synthesis, to other compartments, and its transbilayer asymmetry must ...
arxiv   +1 more source

Subcellular localization of the antidepressant-sensitive norepinephrine transporter

open access: yesBMC Neuroscience, 2009
Background Reuptake of synaptic norepinephrine (NE) via the antidepressant-sensitive NE transporter (NET) supports efficient noradrenergic signaling and presynaptic NE homeostasis.
Winder Danny G   +7 more
doaj   +1 more source

Transport Phenomena in Fluid Films with Curvature Elasticity [PDF]

open access: yesJ. Fluid Mech. 905 (2020) A8, 2020
Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of the membrane.
arxiv   +1 more source

A guide to plasma membrane solute carrier proteins

open access: yesThe FEBS Journal, 2020
This review aims to serve as an introduction to the solute carrier proteins (SLC) superfamily of transporter proteins and their roles in human cells. The SLC superfamily currently includes 458 transport proteins in 65 families that carry a wide variety ...
Mattia D. Pizzagalli   +2 more
semanticscholar   +1 more source

Peroxisome population control by phosphoinositide signaling at the endoplasmic reticulum‐plasma membrane interface

open access: yesTraffic : the International Journal of Intracellular Transport, 2023
Phosphoinositides are lipid signaling molecules acting at the interface of membranes and the cytosol to regulate membrane trafficking, lipid transport and responses to extracellular stimuli. Peroxisomes are multicopy organelles that are highly responsive
Barbara Knoblach, R. A. Rachubinski
semanticscholar   +1 more source

Multicompartmental secretion of ascorbate and its dual role in dopamine beta-hydroxylation.

open access: yesAmerican Journal of Clinical Nutrition, 1991
The neurobiological functions of ascorbate have both intra- and extracellular sites of action. Intracellularly, it participates predominantly in enzymic and transport reactions for neurotransmitter and hormone biosynthesis.
E. Diliberto, A J Daniels, O H Viveros
semanticscholar   +1 more source

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