Results 11 to 20 of about 28,537 (146)

Organic Cation Transporter 3: A Cellular Mechanism Underlying Rapid, Non-Genomic Glucocorticoid Regulation of Monoaminergic Neurotransmission, Physiology, and Behavior [PDF]

, 2018
Corticosteroid hormones act at intracellular glucocorticoid receptors (GR) and mineralocorticoid receptors (MR) to alter gene expression, leading to diverse physiological and behavioral responses.
Gasser, Paul J., Lowry, Christopher A.
core   +2 more sources

Organic Cation Transporter 3 (OCT3) Is Localized to Intracellular and Surface Membranes in Select Glial and Neuronal Cells Within the Basolateral Amygdaloid Complex of Both Rats and Mice [PDF]

, 2016
Organic cation transporter 3 (OCT3) is a high-capacity, low-affinity transporter that mediates corticosterone-sensitive uptake of monoamines including norepinephrine, epinephrine, dopamine, histamine and serotonin. OCT3 is expressed widely throughout the
Chan, June, Gasser, Paul J, Hurley, Matthew M., Pickel, Virginia M.   +3 more
core   +2 more sources

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V, Christoph Handschin, Fatima Bosch, Greco‐Perotto R, Hao Q, Kristoffer Svensson, Marco Colombi, Michael N Hall, Mitsugu Shimobayashi, Sergio Muñoz, Vallerand AL, Verena Albert, Veronica Jimenez   +12 more
core   +4 more sources

[6]-Gingerol, from Zingiber officinale, potentiates GLP-1 mediated glucose-stimulated insulin secretion pathway in pancreatic β-cells and increases RAB8/RAB10-regulated membrane presentation of GLUT4 transporters in skeletal muscle to improve hyperglycemia in Leprdb/db type 2 diabetic mice [PDF]

, 2017
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give ...
Akhter, Farjana, Hannan, J.M.A., Hossain, Mohammad Tashnim, Kabir, Ashraf Ul, Mahzabeen, Sinayat, Mohsin, Md. Nurul Absar Bin, Muna, Ishrat Aklima, Razu, Bodiul Alam, Samad, Mehdi Bin, Unnoor, Naziat   +9 more
core   +2 more sources

Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue. [PDF]

, 1981
Two different monoclonal antibodies, characterized initially as binding synaptic terminal regions of rat brain, bind a 65,000-dalton protein, which is exposed on the outer surface of brain synaptic vesicles. Immunocytochemical experiments at the electron
Matthew, WD, Reichardt, LF, Tsavaler, L
core   +2 more sources

Further Characterization of Dopamine Release by Permeabilized PC 12 Cells [PDF]

, 1987
Rat pheochromocytoma cells (PC 12) permeabilized with staphylococcal α-toxin release [3H]dopamine after addition of micromolar Ca2+. This does not require additional Mg2+-ATP (in contrast to bovine adrenal medullary chromaffin cells).
Ahnert-Hilger G., Bader M. F., Bader M. F., Baker P. F., Bhakdi S., Bhakdi S., Brooks J. C., Dunn L. A., Ekerdt R., Flodgaard H., Gratzl M., Gudrun Ahnert-Hilger, Lowry O. H., Manfred Gratzl, Rubin R. P., Sillen L. G., Simon W., Wadstrom T., Wilson S. P.   +18 more
core   +1 more source

Cloning, expression, and localization of a rat brain high-affinity glycine transporter [PDF]

, 1992
A cDNA clone encoding a glycine transporter has been isolated from rat brain by a combined PCR and plaque-hybridization strategy. mRNA synthesized from this clone (designated GLYT1) directs the expression of sodium-and chloride-dependent, high-affinity ...
Brecha, Nicholas, Davidson, Norman, Guastella, John, Lester, Henry A., Weigmann, Christine   +4 more
core   +1 more source

Rat white adipocytes activate p85/p110 PI3K and induce PM GLUT4 in response to adrenoceptor agonists or aluminum fluoride [PDF]

, 2016
Adipocyte responses to adrenergic and ß-adrenoceptor(-AR) (adrenoceptor) regulation are not sufficiently understood, and information helpful for elucidating the adrenoceptor-responsive machinery is insufficient.
Nomura, Y, Ohsaka, Y
core   +1 more source

GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRET [PDF]

, 2009
The mouse γ-aminobutyric acid (GABA) transporter mGAT1 was expressed in neuroblastoma 2a cells. 19 mGAT1 designs incorporating fluorescent proteins were functionally characterized by [^3H]GABA uptake in assays that responded to several experimental ...
Abramoff, Bal, Bal, Bartholomäus, Bauman, Bjerggaard, Blackman, Boudanova, Boyd, Brückner, Chen, Chiu, Chiu, Cole, Corry, Corry, Deken, Doherty, Drenan, Elangovan, Farhan, Farhan, Farhan, Farhan, Feige, Fraser J. Moss, Gauthier, Geiser, Gordon, Guastella, Harris, Hastrup, Henry A. Lester, Hess, Holton, Hu, Hung, Imoukhuede, Jares-Erijman, Jia Hu, Joanna L. Jankowsky, Just, Kanner, Kanner, Kerschensteiner, Khakh, Kilic, Kimberly Scott, Korkhov, Kuryatov, Lakowicz, Lakowicz, Lester, Lester, Li, Lin, Loder, Loo, Madsen, Mager, Manley, Mazei-Robison, McHugh, Melikian, Michael W. Quick, Miranda, Miranda, Morel, Munro, Nashmi, Nashmi, Ormö, P.I. Imoukhuede, Quick, Raicu, Raicu, Ramamoorthy, Reiterer, Reith, Riven, Rizzo, Roux, Rudnick, Rudnick, Sallette, Schmid, Scholze, Sekar, Sheng, Son, Soragna, Sorkina, Spudich, Tadross, Taunton, Tokunaga, Torres, Torres, Wallrabe, Wang, Whitworth, Xia, Yamashita, Zacharias, Zahniser, Zhang   +105 more
core   +3 more sources

Preferential localization of a vesicular monoamine transporter to dense core vesicles in PC12 cells. [PDF]

, 1994
Neurons and endocrine cells have two types of secretory vesicle that undergo regulated exocytosis. Large dense core vesicles (LDCVs) store neural peptides whereas small clear synaptic vesicles store classical neurotransmitters such as acetylcholine ...
Edwards, RH, Evans, CJ, Liu, Y, Nirenberg, MJ, Pickel, VM, Schweitzer, ES   +5 more
core