Results 71 to 80 of about 28,537 (146)

USSR Space Life Sciences Digest, issue 6 [PDF]

open access: yes
This is the sixth issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 54 papers recently published in Russian language periodicals and bound collections and of 10 new Soviet monographs.
Hooke, L. R.   +3 more
core   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 4, 26 January 2026.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao   +2 more
wiley   +1 more source

Microfabricated Neural Biosensors for Detection of Neurotransmitters, Biomarkers, and Small Molecules: Emerging Trends on Self‐Sustained Systems and Energy Harvesting

open access: yesAdvanced Sensor Research, Volume 5, Issue 1, January 2026.
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley   +1 more source

CARD9 Conveys Pancreatic Islet Sympathetic Nervous β2 Signals to Reshape Macrophage Creatine Metabolism in Type 1 Diabetes

open access: yesAdvanced Science, Volume 13, Issue 3, 14 January 2026.
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan   +12 more
wiley   +1 more source

Acute Stress Attenuates Hepatic Ischemia–Reperfusion Injury via Hypothalamic CRH Neuron‐Induced HPA Axis Activation

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 1, January 2026.
This study demonstrates the protective effect of acute restraint stress (ARS) against hepatic ischemia–reperfusion injury (HIRI) in mice and investigates its specific neuroendocrine mechanisms. During ARS, excitability of PVNCRH neurons significantly increases, which drives HPA axis to release corticosterone, thereby reducing hepatic inflammation and ...
Xiaoqi Lin   +12 more
wiley   +1 more source

Oroxylum indicum (L.) Bark Ameliorates Anxiety and Depression: Evidence From Experimental and Computational Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 1, January 2026.
The study evaluated the antioxidant and neuropharmacological effects of Oroxylum indicum bark (MOIB), identifying 20 phytochemicals through GC–MS analysis. MOIB exhibited anxiolytic, sedative, and antidepressant effects in various behavioral tests, with two compounds (CID 550198 and CID 10393) showing strong binding affinities to targeted receptors and
Md. Aktaruzzaman   +12 more
wiley   +1 more source

Astatine‐211—Towards In Vivo Stable Astatine‐211 Labeled Radiopharmaceuticals and Their (Pre)Clinical Applications

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 203-237, January 2026.
ABSTRACT Targeted radioligand therapy has emerged as a promising treatment option for eradicating advanced cancer forms. α‐Emitters are considered particularly promising as they can obliterate (micro)‐metastases. The α‐emitter astatine‐211 (211At) has experienced increased interest due to its favorable decay properties.
Marius Müller   +5 more
wiley   +1 more source

Navigating Solute Carrier Transporters—A Comprehensive Review of Functionalized Small Molecule Probes for Target Identification and Characterization

open access: yesMedicinal Research Reviews, Volume 46, Issue 1, Page 238-271, January 2026.
ABSTRACT Solute carrier transporters (SLCs) are integral membrane proteins that play pivotal roles in maintaining cellular homeostasis by mediating the transport of a diverse range of substrates across cell membranes. With their involvement in fundamental physiological processes such as nutrient uptake, neurotransmitter signaling, and drug transport ...
Majlen A. Dilweg   +3 more
wiley   +1 more source

Poration by alpha-toxin and streptolysin O [PDF]

open access: yes, 1989
Ahnert-Hilger, Gudrun   +3 more
core   +1 more source

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