Results 81 to 90 of about 28,537 (146)
Pulmonary Circulation, Volume 16, Issue 1, January 2026.ABSTRACT The typical pathology of pulmonary hypertension (PH) is characterized by pulmonary vasoconstriction and irreversible pulmonary vascular remodeling. Vascular remodeling is the process of structural changes and cellular rearrangement of blood vessels due to injury and is a significant factor in conditions such as PH.
Yuefu Zhao +10 more
wiley +1 more source
British Journal of Pharmacology, Volume 183, Issue 1, Page 171-188, January 2026.Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin +6 more
wiley +1 more source
Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones [PDF]
, 2001 Microvesicles in endocrine cells are the morphological and functional equivalent of neuronal synaptic vesicles. Microvesicles accumulate various neurotransmitters through a transmitter-specific vesicular transporter energized by vacuolar H+-ATPase.
Hayashi, Mitsuko +5 more
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Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale
Geriatrics &Gerontology International, Volume 26, Issue 1, January 2026.ABSTRACT The increased anticholinergic burden caused by medications in older adults is one of the adverse drug reactions of particular concern, as it can exacerbate the onset of geriatric syndromes or induce cognitive dysfunction, and is also related to the issue of polypharmacy.
Masaki Mogi +4 more
wiley +1 more source
Physiologic impact of circulating RBC microparticles upon blood-vascular interactions [PDF]
, 2018 Doctor, Allan +2 more
core +2 more sources
Trained Immunity and Cardiovascular Risk: An Immunological Perspective
Immunological Reviews, Volume 337, Issue 1, January 2026.ABSTRACT Systemic inflammation is a key driver of atherogenesis and its complications. While anti‐inflammatory therapies targeting pathways such as IL‐1β and IL‐6 have shown promise in established atherosclerotic cardiovascular disease (ASCVD), potential systemic effects raise concerns about immune suppression and infection, underscoring the need for ...
Katherine A. Boden +3 more
wiley +1 more source
The Use of LeuT as a Receptor Model for Antidepressant Development [PDF]
, 2010 Selective serotonin re-uptake inhibitors (SSRIs) have been considered to be promising drugs in psychiatric practice because of their selectivity to serotonin re-uptake transporter (SERT).
Rustanti, L. (Lina)
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Lethal Case of Bourbon Virus Leading to Shock and ECMO Utilization
Case Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.We present a lethal case of Bourbon virus infection in a 63‐year‐old Caucasian, diabetic male who was previously in good health. The patient had spent time in the wooded areas of Bourbon County, Kansas, and removed three ticks from his body 5 days prior to presentation.
Allianna Mitchell +7 more
wiley +1 more source
Working note-book for the practical classes on biochemistry [PDF]
, 2013 БИОХИМИ
Buyanova, S. V., Konevalova, N. Yu.
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The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease
Journal of Tropical Medicine, Volume 2026, Issue 1, 2026.Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira +2 more
wiley +1 more source