Results 91 to 100 of about 188,346 (313)
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Introduksjon: 25 år med hardt EØS-arbeid: Fra venterom til permanent oppholdssted?
Internasjonal Politikk, 2019 I denne introduksjonsartikkelen viser Ulf Sverdrup at Norge er blitt forandret gjennom EØS-avtalen, men også hvordan den med sine mangler og svakheter i all hovedsak har vært en suksess, og at Norges avtaler i det store og hele har ivaretatt norske ...
Ulf Sverdrup
doaj +1 more source
Structural analyses of features in cultural landscapes based on historical cadastral maps and GIS [PDF]
, 2005 A landscape may appear to be ancient and to contain old man-made structures even if this is not the whole truth. Structures are moved, removed, replaced and added over the years. New users introduce new land use and management regimes.
Domaas, Stein Tage
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A Nanoparticle‐Integrated Complete Manufacturing Pipeline of Chemically Engineered Exosomes
Advanced Science, EarlyView.We report a novel manufacture technology of chemically engineered exosomes. The four steps of manufacturing, i.e., biogenesis, loading, isolation, and storage, are integrated by the use of a nanoparticle. The manufacture technology incorporates three innovative components, i.e., a new nano‐bio effect, a new composite nanoparticle, and a new isolation ...
Xiaowei Wen +13 more
wiley +1 more source
ANIPLAN: Planning for better animal health and welfare [PDF]
It is a main goal for organic livestock farming that animals should always have excellent health and welfare. However, there are indications that this is not always guaranteed even though organic standards are being followed.
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Hvor viktig er rederiskatteordningen for å beholde rederiene i Norge? [PDF]
, 2012 Temaet i denne utredningen er beskatning av rederier. I 1996 ble det for første gang innført særregler for rederibeskatning og regelverket har siden den gang vært gjenstand for flere revideringer.
Augustinussen, Isabel +1 more
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Advanced Science, EarlyView.Climate change reshapes the spatial alignment between crop production and environmental resources. Using multi‐source data and a crop model, integrated climatic, water, and soil endowments for maize and wheat are quantified and compared with harvest distributions.
Zheng'e Su +13 more
wiley +1 more source
β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma
Advanced Science, EarlyView.β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto +20 more
wiley +1 more source
Improved welfare in sheep production.Preventive measures, disease resistance and robustness related to tick-borne fever in sheep [PDF]
The greatest welfare challenges for sheep during grazing are tick-borne fever (TBF), blow-flies, alveld and predators. Production losses on tick infested pastures are substantial, and it is expected that more than 300 000 lambs/sheep are affected by TBF.
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, 2010 The concept of mixed language has recently gained some popularity, to my mind for no good reason. It is unclear how a mixed language can be distinguished from the product of extensive borrowing or relexification.
Kortlandt, Frederik H. H.
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