Results 201 to 210 of about 188,346 (313)

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Further Insight in the High Selectivity of Pb²⁺ Removal over Cd²⁺ in Natural and Dealuminated Rich-Clinoptilolite. [PDF]

Int J Mol Sci
Durán-Avendaño YS, Hernández NC, Ruiz-Salvador AR, Abatal M.   +3 more
europepmc   +1 more source

Impact of secured prescription implementation on ambulatory pregabalin use in France: A regional assessment in the French Nouvelle‐Aquitaine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The French authorities mandated the use of secure prescriptions for pregabalin on May 2021. This study aimed to evaluate the impact of this measure on pregabalin use and misuse in Nouvelle‐Aquitaine, a southwestern French region with around six million inhabitants.
Maika Munech‐Herran, Véronique Moysan, Bruno Lescarret, Clément Mathieu, Antoine Pariente, Nicolas Rousselot   +5 more
wiley   +1 more source

GLU24/7 study: cardiometabolic health risk factors in night shift workers - protocol for a 2-year longitudinal study in an industrial setting in Norway. [PDF]

BMJ Open
Alsaedi S, Skogstad M, Haugen F.
europepmc   +1 more source

The evolving therapeutic landscape of spinal muscular atrophy – A scoping review of investigational agents, emerging delivery technologies and strategic innovations

British Journal of Clinical Pharmacology, EarlyView.
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić, Patrick Eustaquio, Elvira Meni Maria Gkrinia, Ivana Stević, Eugen Javor, Yun Wah Lam, Slobodan Janković, Dinko Vitezić   +7 more
wiley   +1 more source

Childhood neglects: intimate partner violence in PTSD-SUD comorbid patients treated with narrative exposure therapy. [PDF]

Eur J Psychotraumatol
Nolasco Ferreira V, Vigfusdottir J, Breivik E, Jonsbu E, Bell-Mizori AR, Domogalla SA, Tokovska M.   +6 more
europepmc   +1 more source

Use of antiemetics in early pregnancy 2012–2022: A cross‐sectional study

British Journal of Clinical Pharmacology, EarlyView.
Aim Nausea and vomiting in pregnancy impact quality of life, yet many pregnant women feel dismissed by healthcare professionals, despite the safety of first‐line antiemetic treatments for both mother and fetus. Therefore, this study aims to describe the prevalence of patient‐reported antiemetic use in early pregnancy in Copenhagen, Denmark, the changes
Katrine Bak Wraae, Nanna Roed Ballegaard, Mie Lærkeholm Hede, Line Buchgreitz, Ane Lilleøre Rom, Hanne Kristine Hegaard, Nina Olsén Nathan   +6 more
wiley   +1 more source

JAK inhibitors remove innate immune barriers facilitating viral propagation. [PDF]

NAR Mol Med
Ravlo E, Ianevski A, Skipperstøen MN, Lysvand H, Schjølberg JO, Solheim O, Wang W, Kissova M, Vestvik M, Vapalahti O, Smura T, Vauhkonen H, Oksenych V, Weber F, Strand M, Evander M, Malmring JF, Afset JE, Bjørås M, Kainov DE.   +19 more
europepmc   +1 more source

Trends in age‐sex‐specific prevalence and incidence of antidepressant dispensation in the Nordic countries: a systematic review

British Journal of Clinical Pharmacology, EarlyView.
Differences in antidepressant dispensation across the Nordic countries have been reported, but existing reviews are based on older data. We conducted a systematic review of population‐based studies reporting prevalence and/or incidence of antidepressant dispensation in the Nordic countries.
Marcel Ballin, Paulina Tuvendal, Carola Bardage, Mats Persson, Mats Talbäck, Rickard Ljung   +5 more
wiley   +1 more source

Concentrated ERP for Patients With Difficult-to-Treat OCD: Insight as a Predictor of Acute and Long-Term Outcomes. [PDF]

Depress Anxiety
Tjelle K, Hansen B, Solem S, Wheaton MG, Kvale G, Hagen K.   +5 more
europepmc   +1 more source