Results 121 to 130 of about 16,014,283 (355)
LifeGout is an inflammatory arthritis triggered by monosodium urate crystal deposition, especially in obese patients. However, distinctions between the characteristics of obese and non-obese patients with gout remain unclear.
Sung Soo Ahn +6 more
doaj +1 more source
Development of a normal tissue complication probability (NTCP) model for radiation-induced hypothyroidism in nasopharyngeal carcinoma patients [PDF]
, 2018 Ren Luo +8 more
openalex +1 more source
How normal is the "normal" state of superconducting cuprates? [PDF]
, 2004 High magnetic field studies of the cuprate superconductors revealed a non-BCS temperature dependence of the upper critical field $H_{c2}(T)$ determined resistively by several groups.
Alexandrov, A. S., Zavaritsky, V. N.
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
ANTROPOLOGÍA Y ALTERIDAD. DE LA NATURALEZA HUMANA A LA NORMALIDAD SOCIAL
Daimon, 1996 La Antropología, en cuanto «ciencia de la cultura», nace como mirada hacia el otro. La composición de esta mirada está sostenida por la nueva distribución que hace el pensamiento europeo de sus propios espacios de lo normal y lo patológico.
José Lorite Mena
doaj
Anales de la Facultad de Medicina, 2014 Hace muchos años, exactamente desde 1877, en un caso de Mal de Bright, Gordon pudo registrar los movimientos corporales debidos a los impactos de la contracción cardíaca, de la circulación sanguínea y de su propagación. Así, este fenómeno entró en el ambiente del conocimiento científico.
openaire +3 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source