Results 241 to 250 of about 16,014,283 (355)

Automated ECG Report as a Factor in the Clinical Decision Pathway for Acute Chest Pain in the Emergency Department. [PDF]

Cureus
Sankaranarayanan AK, AlNajjar F, Musa A, Kuthbudeen MW, Abdul Wahab AG.   +4 more
europepmc   +1 more source

Required coefficient of friction during turning at self-selected slow, normal, and fast walking speeds

, 2014
Peter C. Fino, Thurmon E. Lockhart
openalex   +1 more source

Campus Comment, December 1929 [PDF]

, 1928
Bridgewater State Normal School
core   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Methionine Restriction Must Be Continuously Maintained to Selectively Inhibit Cancer Cells Co-cultured With Normal Cells. [PDF]

Cancer Diagn Progn
Kang BM, Han Q, Li S, Kim JS, Mizuta K, Asano Y, Miyashi Y, Bouvet M, Hoffman RM.   +8 more
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

A body shape index and sarcopenia risk in middle-aged and older adults: evidence from the China Health and Retirement Longitudinal Study. [PDF]

Eur J Med Res
Shang H, Deng Z, Lian Y, Ai Y, Li G.
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Normal Pituitary Gland Showing an Intratumoral Septal Structure in a Nonfunctioning Pituitary Neuroendocrine Tumor: Illustrative Case. [PDF]

NMC Case Rep J
Ushiki M, Yamaguchi R, Tosaka M, Inoshita N, Yamazaki A, Saito T, Shimauchi-Otaki H, Aishima K, Shimizu T, Nakata S, Yokoo H, Yoshimoto Y, Oya S.   +12 more
europepmc   +1 more source

Normal Gazette, November 1888 [PDF]

, 1888
Normal Gazette Staff
core   +1 more source