Results 281 to 290 of about 16,014,283 (355)

New-onset refractory status epilepticus associated with Sjögren's disease. [PDF]

BMJ Neurol Open
Lim GZ, Kwok JKG, Fan Z, Koh NWC, Lee JS, Yeo T.   +5 more
europepmc   +1 more source

Normal Gazette, December 1888 [PDF]

, 1888
Normal Gazette Staff
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

Molecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek, Jenny Sprooten, Abhishek D. Garg   +2 more
wiley   +1 more source

Normal Gazette, January 1889 [PDF]

, 1889
Normal Gazette Staff
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Understanding the Impact of Weight on Quality of Life and Willingness to Pay for Obesity Management in the APAC Region. [PDF]

Clin Obes
Ko HJ, Kapoor N, Garcia MM, Jung SG, Romano JGU, Hocking SL.   +5 more
europepmc   +1 more source

Normal Gazette, April 1888 [PDF]

, 1888
Normal Gazette Staff
core   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Sustained HIF activation in adult cardiomyocytes show transient beneficial effect in murine HFpEF model. [PDF]

Eur Heart J Open
Sawaki D, Isagawa T, Sato S, Sato T, Semba H, Sugimoto H, Ono K, Chuluun-Erdene A, Pham TT, Tanaka R, Kawakami T, Ito M, Minatsuki S, Higashikuni Y, Asagiri M, Manabe I, Kohro T, Kuchimaru T, Imai Y, Takeda N.   +19 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source