Results 141 to 150 of about 1,176,811 (287)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
On normal approximate spectrum, III
Proceedings of the Japan Academy, Series A, Mathematical Sciences, 1972 Fujii, Masatoshi, Tamaki, Kazuhiro
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
An improved QAOA algorithm based on multi-angle and RY-assisted structure
Tongxin xuebaoThe standard quantum approximate optimization algorithm (QAOA) has a limited expressive power in shallow circuits, whereas naively increasing the number of layers leads to greater quantum circuit depth and higher noise sensitivity.
Tian-Yu Ye, Peng-Hui Ma, Zhi-Gang Gan
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Efficient Pattern Modeling Method for Parabolic Cylindrical Antennas Incorporating Multi-Source Structural Errors. [PDF]
Sensors (Basel)Xue S, Liang W, Zhu M, Ren S.
europepmc +1 more source
Approximation of Normal Cycles
, 2003 This report deals with approximations of geometric data defined on a hypersurf- ace of the Euclidean space E^n. Using geometric measure theory, we evaluate an upper bound on the flat norm of the difference of the normal cycle of a compact subset of E^n whose boundary is a smooth (closed oriented embedded) hypersurface, and the normal cycle of a compact
Cohen-Steiner, David, Morvan, Jean-Marie
openaire +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source